# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA708982 | B | Affinity constant measured against M4 muscarinic receptor rat NG108-15 cells | 4 | ALA1126912 | cell-based format | Scientific Literature | ||
2. | ALA746612 | F | Inhibitory activity against [3H]-cyclic AMP accumulation in CHO transfected cells mediated by Muscarinic acetylcholine receptor M4 | 4 | ALA1131242 | cell-based format | Scientific Literature | ||
3. | ALA746613 | B | Inhibition of binding of [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M4 in rat cerebral cortical membranes at 300 uM concentration | 1 | ALA1131242 | cell membrane format | Scientific Literature | ||
4. | ALA872752 | B | Inhibition of binding of [3H]quinuclidinyl benzilate to muscarinic receptors in membranes of CHO cells transfected with Muscarinic acetylcholine receptor M4 | 1 | ALA1131242 | cell-based format | Scientific Literature | ||
5. | ALA746614 | B | Compound was evaluated for the affinity at the cloned radio labelled Muscarinic acetylcholine receptor M4 | 4 | ALA1131247 | single protein format | Scientific Literature | ||
6. | ALA746615 | B | In vitro binding affinity towards Muscarinic acetylcholine receptor M4 using [3H]QNB as radioligand from rat heart tissue | 3 | ALA1128447 | single protein format | Scientific Literature | ||
7. | ALA746616 | F | Potency assessed to inhibit cAMP levels in rat striatum, for blocking oxotremorine-M, in functional assay for Muscarinic acetylcholine receptor M4 | 1 | ALA1126442 | tissue-based format | Scientific Literature | ||
8. | ALA746617 | B | Inhibition of binding of [3H]N-Methyl-scopolamine to muscarinic acetylcholine receptor M4 of rat heart NG108-15 cells | 14 | ALA1125581 | cell-based format | Scientific Literature | ||
9. | ALA745525 | B | Inhibition of binding of [3H]N-Methyl-scopolamine to muscarinic acetylcholine receptor M4 of rat heart NG108-15 cells | 22 | ALA1125581 | cell-based format | Scientific Literature | ||
10. | ALA745526 | B | Inhibition of binding of [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M4 in rat cerebral cortical membranes | Rattus norvegicus | 7 | ALA1131242 | cell membrane format | Scientific Literature | |
11. | ALA745527 | B | Inhibition of binding of [3H]N-Methyl-scopolamine to Muscarinic acetylcholine receptor M4 of NG108-15 cells. | 10 | ALA1125581 | cell-based format | Scientific Literature | ||
12. | ALA745528 | B | The compound was tested for the inhibition of binding of [3H]N-Methyl-scopolamine to muscarinic acetylcholine receptor M4 of NG108-15 cells; ND denotes not determined | 3 | ALA1125581 | cell-based format | Scientific Literature | ||
13. | ALA745529 | B | Inhibition of NG 108-15 binding to Muscarinic acetylcholine receptor M4 | Rattus norvegicus | 12 | ALA1131294 | single protein format | Scientific Literature | |
14. | ALA745065 | B | Inhibition of binding of [3H]N-methylscopolamine to Muscarinic acetylcholine receptor M4 in NG 108-15 cell homogenates | 6 | ALA1151491 | cell-based format | Scientific Literature | ||
15. | ALA745067 | B | Percent inhibition against muscarinic acetylcholine receptor M4 from NG108-15 cell line | 39 | ALA1124832 | cell-based format | Scientific Literature | ||
16. | ALA745068 | B | Binding affinity at muscarinic acetylcholine receptor M4 from NG108-15 cell line in presence of [3H]-NMS | 39 | ALA1124832 | cell-based format | Scientific Literature | ||
17. | ALA915878 | B | Displacement of radiolabeled atropine from rat brain muscarinic M4 receptor at 10 uM | Rattus norvegicus | 2 | ALA1143001 | assay format | Scientific Literature | |
18. | ALA930976 | F | Antagonist activity at rat muscarinic M4 receptor expressed in CHO cells by calcium mobilization assay | Rattus norvegicus | 12 | ALA1143155 | cell-based format | Scientific Literature | |
19. | ALA932108 | B | Displacement of [3H]NMS from rat muscarinic M4 receptor expressed in CHO cells | Rattus norvegicus | 2 | ALA1143155 | cell-based format | Scientific Literature | |
20. | ALA957799 | F | Activation of rat muscarinic M4 receptor expressed in CHO cells coexpressing chimeric Gqi5 protein assessed as potentiation of acetylcholine-induced intracellular Ca2+ mobilization | Rattus norvegicus | 2 | ALA1136933 | cell-based format | Scientific Literature |