# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA753513 | B | Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | 10 | single protein format | Scientific Literature | |||
2. | ALA754113 | B | Binding affinity to nucleotide-binding domain (NBD2) of P-Glycoprotein | Mus musculus | 8 | single protein format | Scientific Literature | ||
3. | ALA754114 | B | Percent of maximal quenching fluorescence for binding analysis to nucleotide-binding domain (NBD2) of P-Glycoprotein was determined | Mus musculus | 8 | single protein format | Scientific Literature | ||
4. | ALA755828 | F | Inhibition of P-glycoprotein, mouse L-mdr1a expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay | 28 | cell-based format | Scientific Literature | |||
5. | ALA754162 | F | P-gp activity was measured by a direct transport assay, using polarized LLC-MDR1 epithelial cells | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
6. | ALA754163 | F | P-gp activity was measured by a direct transport assay, using polarized LLC-PK1 epithelial cells | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
7. | ALA754164 | F | P-gp activity was measured by a direct transport assay, using polarized LLC-mdr1a epithelial cells | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
8. | ALA754165 | B | In vitro inhibitory activity against P-glycoprotein expressed in murine mammary carcinoma (EMT6/AR1.0 cell line) in accumulation assay | 29 | assay format | Scientific Literature | |||
9. | ALA754166 | B | Inhibition of P-glycoprotein in murine mammary carcinoma (EMT6/AR1.0) cells | Mus musculus | 10 | assay format | Scientific Literature | ||
10. | ALA751606 | B | Inhibitory activity against P-glycoprotein expressed in murine mammary carcinoma (EMT6/AR1.0 cell line) in single-dose potentiation assay | 39 | assay format | Scientific Literature | |||
11. | ALA751607 | B | Inhibitory activity against P-glycoprotein expressed in murine mammary carcinoma (EMT6/AR1.0 cell line) in single-dose potentiation assay; nd = not determined | 7 | assay format | Scientific Literature | |||
12. | ALA751608 | B | Inhibitory activity against P-glycoprotein expressed in murine mammary carcinoma (EMT6/AR1.0 cell line) in single-dose potentiation assay; nd=not determined | 1 | assay format | Scientific Literature | |||
13. | ALA857698 | B | Inhibitory activity against Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell line in accumulation assay; nd = not determined | 1 | assay format | Scientific Literature | |||
14. | ALA2076908 | F | TP_TRANSPORTER: transepithelial transport (basal to apical) in mdr1a-expressing LLC-PK1 cell | 1 | cell-based format | TP-search Transporter Database | |||
15. | ALA2076909 | F | TP_TRANSPORTER: tissue concentration in mdr1a(-/-) mouse | Mus musculus | 1 | organism-based format | TP-search Transporter Database | ||
16. | ALA2076910 | F | TP_TRANSPORTER: no influence on tissue distribution in mdr1a(-/-) mouse | Mus musculus | 1 | organism-based format | TP-search Transporter Database | ||
17. | ALA2076911 | F | TP_TRANSPORTER: no change in plasma concentration in mdr1a(-/-) mouse | Mus musculus | 1 | organism-based format | TP-search Transporter Database | ||
18. | ALA2076912 | F | TP_TRANSPORTER: no change in liver concentration in mdr1a(-/-) mouse | Mus musculus | 1 | organism-based format | TP-search Transporter Database | ||
19. | ALA2076913 | F | TP_TRANSPORTER: no change in kidney concentration in mdr1a(-/-) mouse | Mus musculus | 1 | organism-based format | TP-search Transporter Database | ||
20. | ALA2076914 | F | TP_TRANSPORTER: no change in brain concentration in mdr1a(-/-) mouse | Mus musculus | 1 | organism-based format | TP-search Transporter Database |