#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA878552	F	Ability to decrease plasma insulin levels in mouse at a dose 100 mg/kg/day	Mus musculus	27		organism-based format	Scientific Literature
2.	ALA745799	F	In vivo ability to decrease plasma glucose levels in diabetic C57BL/KsJ ob/ob mouse at a dose 100 mg/kg/day	Mus musculus	27		organism-based format	Scientific Literature
3.	ALA877453	B	Binding affinity for mouse protein-tyrosine phosphatase 1B (PTP1B) expressed in COS 7 cells	Mus musculus	8		cell-based format	Scientific Literature
4.	ALA836246	B	In vitro inhibitory activity against PTP1B at 100 uM 10 min incubation	Mus musculus	23		single protein format	Scientific Literature
5.	ALA2016033	B	Inhibition of PTP1B in mouse C2C12 cells assessed as increase in insulin receptor beta tyrosine phosphorylation at 25 uM	Mus musculus	7		cell-based format	Scientific Literature
6.	ALA2016034	B	Inhibition of PTP1B in mouse C2C12 cells assessed as increase in intracellular 2-deoxyglucose uptake using [3H]glucose as substrate at 25 uM after 90 mins by scintillation counting	Mus musculus	8		cell-based format	Scientific Literature
7.	ALA3102568	B	Inhibition of PTP1B in mouse C2C12 cells assessed as increase of 2-deoxy-D-1,2-[3H]-glucose at 25 uM after 90 mins by beta-scintillation counting	Mus musculus	5		cell-based format	Scientific Literature
8.	ALA3102569	B	Inhibition of PTP1B in mouse C2C12 cells assessed as increase of insulin receptor beta phosphorylation at 25 uM after 90 mins	Mus musculus	9		cell-based format	Scientific Literature
9.	ALA3587905	B	Inhibition of PTP1B in mouse 3T3L1 cells assessed as stimulation of 2-NBDG uptake preincubated for 24 hrs followed by 2-NBDG addition measured after 30 mins by fluorescence reader analysis	Mus musculus	7		cell-based format	Scientific Literature
10.	ALA3587906	B	Inhibition of PTP1B in mouse 3T3L1 cells assessed as stimulation of 2-NBDG uptake at 10 uM preincubated for 24 hrs followed by 2-NBDG addition measured after 30 mins by fluorescence reader analysis relative to control	Mus musculus	3		cell-based format	Scientific Literature
11.	ALA3995110	B	Inhibition of PTP1B in mouse C2C12 cells assessed as increase in phosphorylation of IRbeta at Tyr1162/1163 residues at 50 uM after 30 mins by Western blot method	Mus musculus	6		cell-based format	Scientific Literature
12.	ALA3995112	B	Inhibition of PTP1B in mouse C2C12 cells assessed as increase in phosphorylation of Akt at Ser473 residue at 50 uM after 30 mins by Western blot method	Mus musculus	6		cell-based format	Scientific Literature
13.	ALA4021013	B	Inhibition of PTP1B in mouse C2C12 cells assessed as increase in IRS1 phosphorylation at Y632 residues at 0.25 to 1 uM after 8 hrs by Western blot analysis	Mus musculus	1		cell-based format	Scientific Literature
14.	ALA4021014	B	Inhibition of PTP1B in mouse C2C12 cells assessed as increase in Akt phosphorylation at S473 residues in mouse C2C12 cells at 0.1 to 1 uM after 8 hrs by Western blot analysis	Mus musculus	1		cell-based format	Scientific Literature
15.	ALA4021021	B	Inhibition of PTP1B in mouse C2C12 cells assessed as increase in IRbeta phosphorylation at Y1146 residues in mouse C2C12 cells at 0.1 to 1 uM after 8 hrs by Western blot analysis	Mus musculus	1		cell-based format	Scientific Literature
16.	ALA4047700	B	Inhibition of PTP1B in differentiated mouse C2C12 cells assessed as upregulation of AMPKalpha phosphorylation at Thr-172 residue by Western blot assay	Mus musculus	1		assay format	Scientific Literature
17.	ALA4047701	B	Inhibition of PTP1B in differentiated mouse C2C12 cells assessed as upregulation of ACC phosphorylation at Ser-79 residue at 20 uM after 30 mins by Western blot assay	Mus musculus	1		assay format	Scientific Literature
18.	ALA4047702	B	Inhibition of PTP1B in differentiated mouse C2C12 cells assessed as upregulation of ACC phosphorylation at Ser-79 residue at 0.2 mM after 30 mins by Western blot assay	Mus musculus	1		assay format	Scientific Literature
19.	ALA4047703	B	Inhibition of PTP1B in differentiated mouse C2C12 cells assessed as upregulation of AMPKalpha phosphorylation at Thr-172 residue at 20 uM after 3 hrs by Western blot assay	Mus musculus	1		assay format	Scientific Literature
20.	ALA4047705	B	Inhibition of PTP1B in differentiated mouse 3T3L1 cells assessed as increase in glucose uptake at 5 to 20 uM after 1 hr by 2-NBDG staining based fluorescence assay	Mus musculus	2		assay format	Scientific Literature