# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1176319 | F | Antagonist activity at rat TRPV2 receptor | Rattus norvegicus | 1 | ALA1177639 | assay format | Scientific Literature | |
2. | ALA1825339 | F | Agonist activity at rat recombinant TRPV2 receptor expressed in HEK293 cells assessed as stimulation of intracellular calcium level using Fluo4-AM dye based fluorimetric assay relative to 4 uM ionomycin | Rattus norvegicus | 2 | ALA1821606 | cell-based format | Scientific Literature | |
3. | ALA1825340 | F | Agonist activity at rat recombinant TRPV2 receptor expressed in HEK293 cells assessed as stimulation of intracellular calcium level using Fluo4-AM dye based fluorimetric assay | Rattus norvegicus | 2 | ALA1821606 | cell-based format | Scientific Literature | |
4. | ALA1825341 | F | Antagonist activity at rat recombinant TRPV2 receptor expressed in HEK293 cells assessed as inhibition of 3 uM lysophosphatidylcholine-induced stimulation of intracellular calcium level using Fluo4-AM dye based fluorimetric assay | Rattus norvegicus | 2 | ALA1821606 | cell-based format | Scientific Literature | |
5. | ALA4143894 | B | Agonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluorescence assay | Rattus norvegicus | 2 | ALA4138251 | cell-based format | Scientific Literature | |
6. | ALA4235225 | B | Agonist activity at rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay relative to ionomycin | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
7. | ALA4235226 | B | Agonist activity at rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
8. | ALA4235227 | B | Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced increase in intracellular calcium level pretreated for 5 mins followed by LPC addition by Fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
9. | ALA4236713 | B | Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM based spectrofluorimetry | Rattus norvegicus | 50 | ALA4229558 | cell-based format | Scientific Literature | |
10. | ALA4236714 | B | Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM based spectrofluorimetry | Rattus norvegicus | 50 | ALA4229558 | cell-based format | Scientific Literature | |
11. | ALA4236715 | B | Non-competitive antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM dependent spectrofluorimetry based Schild analysis | Rattus norvegicus | 3 | ALA4229558 | cell-based format | Scientific Literature | |
12. | ALA4236716 | B | Non-competitive antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM dependent spectrofluorimetry based Schild analysis | Rattus norvegicus | 3 | ALA4229558 | cell-based format | Scientific Literature | |
13. | ALA4377085 | B | Inhibition of YFP-tagged rat TRPV2 expressed in HEK293 cells assessed as reduction in calcium level by fluo-4 dye based fluorescence assay | Rattus norvegicus | 1 | ALA4376804 | cell-based format | Scientific Literature | |
14. | ALA4478090 | B | Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced intracellular calcium accumulation preincubated for 5 mins followed by LPC addition by Fluo-4-AM probe-based spectrofluorimetric assay | Rattus norvegicus | 4 | ALA4477204 | cell-based format | Scientific Literature | |
15. | ALA4478096 | B | Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced intracellular calcium accumulation up to 10 uM preincubated for 5 mins followed by LPC addition by Fluo-4-AM probe-based spectrofluorimetric assay | Rattus norvegicus | 4 | ALA4477204 | cell-based format | Scientific Literature | |
16. | ALA4675876 | B | Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ response preincubated for 5 mins followed by LPC addition by Fluo-4AM dye based fluorescence assay | Rattus norvegicus | 2 | ALA4673241 | cell-based format | Scientific Literature | |
17. | ALA4675877 | B | Agonist activity at rat TRPV2 stably transfected in HEK293 cells assessed as increase in calcium influx in presence of ionomycin by Fluo-4-AM dye based spectrofluorimetric method | Rattus norvegicus | 2 | ALA4673241 | cell-based format | Scientific Literature | |
18. | ALA4675878 | B | Agonist activity at rat TRPV2 stably transfected in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based spectrofluorimetric method relative to ionomycin | Rattus norvegicus | 2 | ALA4673241 | cell-based format | Scientific Literature |