# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA669550 | F | Compound was tested for agonistic activity on rat dorsal root ganglion neurons (thought to express GluR5 receptors) | 4 | tissue-based format | Scientific Literature | |||
2. | ALA669551 | F | Compound was tested for agonistic activity on rat dorsal root ganglion neurons (thought to express GluR5 receptors); not determined | 1 | tissue-based format | Scientific Literature | |||
3. | ALA669552 | F | Agonistic activity of compound on rat dorsal root ganglion cells was expressed as percentage Rmax | 3 | tissue-based format | Scientific Literature | |||
4. | ALA669553 | F | Agonistic activity of compound on rat dorsal root ganglion cells was expressed as percentage Rmax; ND means Not determined | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
5. | ALA698527 | B | Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using [3H]-kainic acid | 8 | single protein format | Scientific Literature | |||
6. | ALA698528 | B | Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using [3H]-kainic acid | 1 | single protein format | Scientific Literature | |||
7. | ALA862719 | F | Antagonism on GLUK5 containing kainate induced depolarization of isolated neonatal rat dorsal root C-fibers | Rattus norvegicus | 18 | assay format | Scientific Literature | ||
8. | ALA862727 | F | Percentage depression of GLUK5 containing kainate induced depolarization on isolated neonatal rat dorsal root C-fibers at 200 uM | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
9. | ALA859852 | F | Ability to inhibit domoic acid-induced increase of calcium in rat HEK293 cells expressing GluR5 | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
10. | ALA904263 | F | Activity at native GLUK5 kainate receptor assessed as antagonism of kainite-induced depolarization of neonatal anaesthetised rat dorsal root fibres | Rattus norvegicus | 14 | assay format | Scientific Literature | ||
11. | ALA920257 | B | Displacement of [3H]SYM 2081 from rat recombinant GluR5 expressed in Sf9 cells | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
12. | ALA1817064 | B | Displacement of [3H]SYM2081 from rat GluK1 expressed in Sf9 cells | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
13. | ALA928080 | B | Activity at rat cloned iGluR5 expressed in human HEK293 cells by calcium imaging assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
14. | ALA928081 | B | Activity at rat cloned iGluR5 expressed in human HEK293 cells by calcium imaging assay relative to L-glutamate | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
15. | ALA1954500 | B | Displacement of [3H]-Kainate from wild type rat GluK1 receptor | Rattus norvegicus | 4 | single protein format | Scientific Literature | ||
16. | ALA1013073 | B | Displacement of [3H]SYM2081 from rat cloned iGluR5 | Rattus norvegicus | 3 | single protein format | Scientific Literature | ||
17. | ALA1013087 | B | Displacement of [3H]SYM2081 from rat recombinant iGluR5 | Rattus norvegicus | 12 | single protein format | Scientific Literature | ||
18. | ALA1028971 | B | Displacement of [3H]SYM2081 from rat recombinant iGluR5(Q)1b expressed in Sf9 cells | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
19. | ALA1059439 | B | Displacement of [3H]SYM from rat recombinant GluR5(Q) RNA-edited isoform expressed in baculovirus infected Sf9 cells | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
20. | ALA1062119 | F | Agonist activity at rat recombinant GluR5(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assay | Rattus norvegicus | 5 | cell-based format | Scientific Literature |