# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA696977 | F | Effective concentration of compound was determined for electrophysiological properties on Ionotropic glutamate receptor AMPA 2 (GluR2) using rat cortical slice model in Xenopus laevis oocytes | 2 | cell-based format | Scientific Literature | |||
2. | ALA697505 | F | The potency at recombinant rat AMPA-R was measured on receptor Ionotropic glutamate receptor AMPA 2 expressed in Xenopus Laevis oocytes | 1 | cell-based format | Scientific Literature | |||
3. | ALA697506 | B | Binding affinity towards Ionotropic glutamate receptor AMPA 2 from rat brain | 1 | assay format | Scientific Literature | |||
4. | ALA919617 | F | Antagonist activity at rat homomeric recombinant GluR2 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLIPR assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
5. | ALA919624 | F | Antagonist activity at rat homomeric recombinant GluR2 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration at 30 uM by FLIPR assay | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
6. | ALA920804 | B | Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
7. | ALA1817063 | B | Displacement of [3H]AMPA from rat GluA2 expressed in Sf9 cells | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
8. | ALA928074 | B | Activity at rat cloned iGluR2 expressed in human HEK293 cells by calcium imaging assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
9. | ALA928075 | B | Activity at rat cloned iGluR2 expressed in human HEK293 cells by calcium imaging assay relative to L-glutamate | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
10. | ALA1036612 | B | Inhibition of rat recombinant GluR2/GluR3 expressed in Xenopus oocytes assessed as inhibition of kainate-induced evoked current at 3 uM by two electrode voltage clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
11. | ALA1028968 | B | Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cells | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
12. | ALA1029764 | F | Agonist activity at cyclothiazide-desensitized rat recombinant flop iGluR2(Q) expressed in Xenopus laevis oocytes by two electrode voltage-clamp electrophysiology method | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
13. | ALA1029765 | F | Agonist activity at cyclothiazide-desensitized rat recombinant flip iGluR2(Q) expressed in Xenopus laevis oocytes by two electrode voltage-clamp electrophysiology method | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
14. | ALA1029772 | F | Agonist activity at rat flip iGluR2(Q) expressed in Xenopus laevis oocytes by whole cell patch-clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
15. | ALA1059436 | B | Displacement of [3H]AMPA from rat recombinant GluR2(R) RNA-edited flop isoform expressed in baculovirus infected Sf9 cells | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
16. | ALA1059444 | F | Agonist activity at rat recombinant GluR2(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assay | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
17. | ALA1059445 | F | Agonist activity at rat recombinant GluR2(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assay relative to glutamic acid | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
18. | ALA1064565 | B | Displacement of [3H]AMPA from wild type rat GluR2 S1S2 ligand binding core | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
19. | ALA1105523 | F | Agonist activity at rat recombinant GluA2 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by Fluo-4/AM staining-based fluorescence assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
20. | ALA1106355 | F | Antagonist activity at rat recombinant GluA2 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by Fluo-4/AM staining-based fluorescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature |