| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA876410 | B | Concentration required for inhibition of serine/threonine protein phosphatase calcineurin (CAN) | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
| 2. | ALA653180 | B | Inhibitory activity against Calcineurin (CaN phosphatase) | Rattus norvegicus | 11 | single protein format | Scientific Literature | ||
| 3. | ALA653182 | B | Compound was evaluated for its inhibitory activity in a calcineurin inhibition assay | 9 | single protein format | Scientific Literature | |||
| 4. | ALA856072 | B | Compound was evaluated for its inhibitory activity in a calcineurin inhibition assay (MOM) | 1 | single protein format | Scientific Literature | |||
| 5. | ALA653183 | B | Compound was evaluated for its inhibitory activity in a calcineurin inhibition assay (MTM) | 1 | single protein format | Scientific Literature | |||
| 6. | ALA653184 | B | Compound was evaluated for its inhibitory activity in a calcineurin inhibition assay (morn) | 2 | single protein format | Scientific Literature | |||
| 7. | ALA655821 | B | Binding affinity to protein phosphatase, calcineurin (CN) was determined | 7 | single protein format | Scientific Literature | |||
| 8. | ALA655822 | B | Inhibitory activity against (calcineurin) was determined | 2 | single protein format | Scientific Literature | |||
| 9. | ALA873191 | B | Inhibitory constant of compound against calcineurin was determined | 1 | single protein format | Scientific Literature | |||
| 10. | ALA1909202 | B | DRUGMATRIX: Protein Serine/Threonine Phosphatase, PPP3CA (Calcineurin, PP2B) enzyme inhibition (substrate: DiFMUP) | Escherichia coli | 871 | single protein format | DrugMatrix | ||
| 11. | ALA1220314 | B | Inhibition of calcineurin-mediated NFAT activation in human Jurkat cells by luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA1220315 | B | Inhibition of calcineurin-mediated NFAT activation in human Jurkat cells measured after 45 min of irradiation with 740 nm light by luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA1220316 | B | Selectivity ratio of IC50 for calcineurin-mediated NFAT activation in human Jurkat cells to IC50 for calcineurin-mediated NFAT activation in human Jurkat cells measured after 45 min of irradiation with 740 nm light | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA1220326 | B | Inhibition of calcineurin-mediated streptavidin-coupled NFAT activation in human Jurkat cells by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA1220327 | B | Inhibition of calcineurin-mediated streptavidin-coupled NFAT activation in human Jurkat cells measured after 45 min of irradiation with 740 nm light by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3870777 | B | Inhibition of recombinant 6His-tagged human calcineurin-alpha expressed in Escherichia coli BL21(DE3/pLysS) assessed as inhibition of calcineurin phosphatase activity by measuring amount of free phosphate at 10 uM preincubated for 20 mins followed by addition of bovine RII phosphopeptide as substrate measured after 30 mins in presence of human calmodulin by malachite green dye-based spectrophotometry relative to DMSO control | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 17. | ALA4824775 | B | Inhibition of human calcineurin activity in PMA/ionomycin-induced human Jurkat cells measured after 44 hrs by Malachite green dye based fast green assay | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
| 18. | ALA4824776 | B | Inhibition of human calcineurin activity in PMA/ionomycin-induced human Jurkat cells at 15 uM measured after 44 hrs by Malachite green dye based fast green assay | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
| 19. | ALA4880890 | B | Protein Serine/threonine Phosphatase, PPP3CA (Calcineurin, PP2B) Eurofins-Panlabs enzyme assay | Homo sapiens | 2 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 20. | ALA5058757 | B | Protein Serine/Threonine Phosphatase, Calcineurin, PP2B Eurofins-Panlabs enzyme assay | Homo sapiens | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt |
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