| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1041781 | B | Inhibition of human Kallikrein 4 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 2. | ALA1044638 | B | Inhibition of kallikrein 4 assessed as residual activity at 10 uM after 10 to 15 mins by fluorescence assay relative to control | 1 | single protein format | Scientific Literature | |||
| 3. | ALA1039260 | B | Inhibition of kallikrein 4 after 10 to 15 mins by fluorescence assay | 1 | single protein format | Scientific Literature | |||
| 4. | ALA3626833 | B | Inhibition of KLK4 (unknown origin) expressed in Sf9 cells at 25 nM using FVQRpNA substrate by spectrophotometry method | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA3627280 | B | Inhibition of KLK4 (unknown origin) expressed in Sf9 cells using FVQRpNA substrate by spectrophotometry method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA3772516 | B | Inhibition of human recombinant KLK4 expressed in Escherichia coli using Bachem I-1120 as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | assay format | Scientific Literature | ||
| 7. | ALA3772706 | B | Reversible inhibition of human recombinant KLK4 expressed in Escherichia coli using Bachem I-1120 as fluorogenic substrate at 100 times IC50 preincubated for 15 mins followed by 100 fold dilution measured for 1 hr by microplate reader analysis | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 8. | ALA4201841 | B | Inhibition of N-terminal FLAG-tagged and C-terminal His tagged pro-KLK4 (unknown origin) expressed in Escherichia coli in presence of thermolysin pre-incubated for 10 mins before Boc-FSR-AMC substrate addition and measured after 20 mins by fluorescence based assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 9. | ALA4201857 | B | Binding affinity to recombinant KLK4 (unknown origin) at 50 uM pre-incubated with conditioned medium for 30 mins by activity-based probe based in-gel fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4330016 | B | Inhibition of KLK4 (unknown origin) expressed in sf9 cells using Ac-FVQR-pNA as substrate preincubated for 30 mins followed by substrate addition and measured for 7 mins by spectrophotometric method | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA4831727 | B | Inhibition of KLK4 (unknown origin) assessed as inhibition of release of AMC fluorescent product using H-VPR-AMC as substrate at 10 uM incubated for 30 mins by microplate reader relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 12. | ALA5213836 | B | Selectivity interaction (Serine protease panel) EUB0000735a KLK4 | Homo sapiens | 1 | single protein format | Literature data from EUbOPEN Chemogenomic Library |
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