# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1044639 | B | Inhibition of kallikrein 5 assessed as residual activity at 10 uM after 10 to 15 mins by fluorescence assay relative to control | 1 | ALA1156023 | single protein format | Scientific Literature | ||
2. | ALA1039261 | B | Inhibition of kallikrein 5 after 10 to 15 mins by fluorescence assay | 1 | ALA1156023 | single protein format | Scientific Literature | ||
3. | ALA1837529 | B | Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by spectrofluorimetric assay | Homo sapiens | 3 | ALA1833973 | single protein format | Scientific Literature | |
4. | ALA1837530 | B | Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis | Homo sapiens | 3 | ALA1833973 | single protein format | Scientific Literature | |
5. | ALA1837533 | B | Competitive inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA1833973 | single protein format | Scientific Literature | |
6. | ALA2090270 | B | Inhibition of human recombinant KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by FRET analysis | Homo sapiens | 5 | ALA2086392 | assay format | Scientific Literature | |
7. | ALA2090274 | B | Competitive inhibition of human KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by Dixon plot analysis | Homo sapiens | 5 | ALA2086392 | assay format | Scientific Literature | |
8. | ALA2339964 | B | Inhibition of Kallikrein-5 (unknown origin) using Z-VVR-AMC substrate incubated for 15 mins prior to substrate addition measured for 2 hrs | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
9. | ALA2339094 | B | Inhibition of Kallikrein-5 (unknown origin) using Z-VVR-AMC substrate assessed as residual activity at 10 uM incubated for 15 mins prior to substrate addition measured for 2 hrs | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
10. | ALA2412637 | B | Binding affinity to human kallikrein 5 assessed as deacylation of enzyme relative to control | Homo sapiens | 2 | ALA2406906 | single protein format | Scientific Literature | |
11. | ALA2412638 | B | Transient inhibition of human kallikrein 5 assessed as spontaneous reactivation up to 6 hrs | Homo sapiens | 1 | ALA2406906 | single protein format | Scientific Literature | |
12. | ALA2412639 | B | Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by double-reciprocal plot analysis | Homo sapiens | 1 | ALA2406906 | single protein format | Scientific Literature | |
13. | ALA2412640 | B | Inhibition of human kallikrein 5 at 296 nM to 1 uM at pH 8 by fluorescence assay | Homo sapiens | 1 | ALA2406906 | single protein format | Scientific Literature | |
14. | ALA2412643 | B | Inhibition of human kallikrein 5 at 0.5 to 8 uM at pH 8 by fluorescence assay | Homo sapiens | 1 | ALA2406906 | single protein format | Scientific Literature | |
15. | ALA2412650 | B | Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assay | Homo sapiens | 7 | ALA2406906 | single protein format | Scientific Literature | |
16. | ALA3100744 | B | Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate at 50 uM after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis | Homo sapiens | 3 | ALA3098059 | single protein format | Scientific Literature | |
17. | ALA3100871 | B | Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis | Homo sapiens | 5 | ALA3098059 | single protein format | Scientific Literature | |
18. | ALA3100875 | B | Reversible inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by fluorescence assay | Homo sapiens | 16 | ALA3098059 | single protein format | Scientific Literature | |
19. | ALA3100882 | B | Inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate at 50 uM after 15 mins by fluorescence assay | Homo sapiens | 11 | ALA3098059 | single protein format | Scientific Literature | |
20. | ALA3100883 | B | Inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 mins by fluorescence assay | Homo sapiens | 5 | ALA3098059 | single protein format | Scientific Literature |