# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA644197 | F | Effective dose required for the action of AMPA receptor antagonistic activity in maximal electroshock anticonvulsant assay | 1 | assay format | Scientific Literature | |||
2. | ALA644198 | B | Binding affinity against AMPA receptor using [3H]AMPA as the radioligand. | 1 | single protein format | Scientific Literature | |||
3. | ALA680873 | F | Potentiation of responses mediated by 100 uM L-glutamate in transfected HEK293 cells expressing human homomeric iGluR4 flip receptors. | 15 | cell-based format | Scientific Literature | |||
4. | ALA680874 | F | % potentiation of responses mediated by 100 uM L-glutamate in human transfected HEK293 cells expressing homomeric iGluR4 flip receptors at a dose of 3 uM. | 13 | cell-based format | Scientific Literature | |||
5. | ALA698777 | B | Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 3 (GluR4o) | Xenopus laevis | 1 | cell-based format | Scientific Literature | ||
6. | ALA698778 | B | Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 4 (GluR4o) | Xenopus laevis | 2 | cell-based format | Scientific Literature | ||
7. | ALA698779 | B | In vitro inhibitory activity against Ionotropic glutamate receptor AMPA 4 of HEK293 cells in FLIPR assay | 2 | cell-based format | Scientific Literature | |||
8. | ALA874140 | B | Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 4 | 3 | single protein format | Scientific Literature | |||
9. | ALA878454 | B | Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 4 expressed in HEK293 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
10. | ALA696661 | B | Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 4 using cell membranes prepared from HEK293 cells | 7 | cell-based format | Scientific Literature | |||
11. | ALA696662 | B | Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 4 in HEK293 cells using [3H]AMPA as radioligand | 4 | cell-based format | Scientific Literature | |||
12. | ALA696664 | B | Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 4 (GluR4) expressed in Sf 9 insect cells | 3 | cell-based format | Scientific Literature | |||
13. | ALA841849 | F | Tested for potentiation towards human iGluR4 receptor expressed in HEK293 cells | 29 | cell-based format | Scientific Literature | |||
14. | ALA829621 | B | Binding affinity for ionotropic Glutamate receptor AMPA 4 expressed in Sf9 cells | 5 | cell-based format | Scientific Literature | |||
15. | ALA863282 | F | Inhibitory effect on glutamate-induced calcium influx at homomeric human GLUA4 receptor expressed in HEK293 cells up to 300 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA865011 | F | Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA4 up to 100 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA865017 | F | Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA4 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA869262 | F | Activity against human GLUR4 flip expressed in HEK293 cells assessed as glutamate-stimulated calcium influx by FLIPR assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
19. | ALA868049 | F | Activity against human GLUR4 flop expressed in HEK293 cells assessed as glutamate-stimulated calcium influx by FLIPR assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
20. | ALA856922 | F | Activity at human recombinant iGluR4 flip expressed in HEK293 cells measured as change in intracellular calcium ion concentration in presence of glutamate by FLIPR assay | Homo sapiens | 25 | cell-based format | Scientific Literature |