# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA680698 | B | Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2 | 5 | ALA1132792 | cell-based format | Scientific Literature | ||
2. | ALA680699 | B | Binding affinity for Excitatory amino acid transporter 2 (EAAT-2) in Glu uptake system | 11 | ALA1135397 | single protein format | Scientific Literature | ||
3. | ALA680704 | F | Potency (100 uM) to induce a transport current in the absence of glutamate in oocytes expressing human excitatory amino acid transporter 2 (EAAT2) | Homo sapiens | 5 | ALA1132792 | cell-based format | Scientific Literature | |
4. | ALA680705 | F | Potency (100 uM) to induce a transport current in the presence of glutamate in oocytes expressing human excitatory amino acid transporter 2 (EAAT2) | Homo sapiens | 5 | ALA1132792 | cell-based format | Scientific Literature | |
5. | ALA880445 | B | Inhibitory concentration against glutamate uptake in oocytes expressing in human Excitatory amino acid transporter 2 | Homo sapiens | 1 | ALA1143635 | cell-based format | Scientific Literature | |
6. | ALA881963 | B | Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2 | Homo sapiens | 27 | ALA1143635 | cell-based format | Scientific Literature | |
7. | ALA881966 | B | Inhibitory concentration against glutamate uptake in MDCK cells expressing in human Excitatory amino acid transporter 2 | Homo sapiens | 1 | ALA1143635 | cell-based format | Scientific Literature | |
8. | ALA859748 | F | Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assay | Homo sapiens | 12 | ALA1141219 | cell-based format | Scientific Literature | |
9. | ALA870601 | B | Activity against human EAAT2 transfected in HEK293 cells | Homo sapiens | 2 | ALA1148598 | cell-based format | Scientific Literature | |
10. | ALA907701 | F | Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assay | Homo sapiens | 3 | ALA1137310 | cell-based format | Scientific Literature | |
11. | ALA907706 | F | Substrate activity at human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assay | Homo sapiens | 2 | ALA1137310 | cell-based format | Scientific Literature | |
12. | ALA907709 | F | Substrate activity at human EAAT2 expressed in HEK293 cells at 1000 uM relative to glutamate by FLIPR membrane potential assay | Homo sapiens | 1 | ALA1137310 | cell-based format | Scientific Literature | |
13. | ALA1016588 | B | Inhibition of glutamate-induced depolarization in human EAAT2 expressed in HEK293 cells by FMP assay | Homo sapiens | 12 | ALA1155081 | cell-based format | Scientific Literature | |
14. | ALA1016591 | B | Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cells | Homo sapiens | 11 | ALA1155081 | cell-based format | Scientific Literature | |
15. | ALA998473 | B | Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells | Homo sapiens | 26 | ALA1140931 | cell-based format | Scientific Literature | |
16. | ALA998476 | B | Activity of human EAAT2 expressed in HEK293 cells up to 100 uM | Homo sapiens | 1 | ALA1140931 | cell-based format | Scientific Literature | |
17. | ALA998479 | B | Activity at human EAAT2 expressed in HEK293 cells assessed as inhibition of Glu-induced fluorescent response by FLIPR membrane potential blue assay | Homo sapiens | 1 | ALA1140931 | cell-based format | Scientific Literature | |
18. | ALA1259928 | B | Inhibition of human GLT1 expressed in HEK293 cells assessed as reduction of [3H]-glutamate uptake at 500 uM after 10 mins by scintillation counting | Homo sapiens | 5 | ALA1255170 | cell-based format | Scientific Literature | |
19. | ALA1259930 | B | Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation counting | Homo sapiens | 15 | ALA1255170 | cell-based format | Scientific Literature | |
20. | ALA1259931 | B | Inhibition of human GLT1 expressed in HEK293 cells assessed as reduction of [3H]-glutamate uptake at 100 uM after 10 mins by scintillation counting relative to control | Homo sapiens | 1 | ALA1255170 | cell-based format | Scientific Literature |