# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA680698 | B | Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2 | 5 | cell-based format | Scientific Literature | |||
2. | ALA680699 | B | Binding affinity for Excitatory amino acid transporter 2 (EAAT-2) in Glu uptake system | 11 | single protein format | Scientific Literature | |||
3. | ALA680704 | F | Potency (100 uM) to induce a transport current in the absence of glutamate in oocytes expressing human excitatory amino acid transporter 2 (EAAT2) | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA680705 | F | Potency (100 uM) to induce a transport current in the presence of glutamate in oocytes expressing human excitatory amino acid transporter 2 (EAAT2) | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA880445 | B | Inhibitory concentration against glutamate uptake in oocytes expressing in human Excitatory amino acid transporter 2 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA881963 | B | Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2 | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
7. | ALA881966 | B | Inhibitory concentration against glutamate uptake in MDCK cells expressing in human Excitatory amino acid transporter 2 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA859748 | F | Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
9. | ALA870601 | B | Activity against human EAAT2 transfected in HEK293 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA907701 | F | Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA907706 | F | Substrate activity at human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA907709 | F | Substrate activity at human EAAT2 expressed in HEK293 cells at 1000 uM relative to glutamate by FLIPR membrane potential assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA2067160 | B | Inhibition of human EAAT2 expressed in HEK293 cells assessed as inhibition of 3[H]-D-Aspartate uptake after 6 mins by scintillation counting method | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
14. | ALA1919951 | B | Inhibition of EAAT2-mediated D-aspartate transport at 100 uM | 2 | single protein format | Scientific Literature | |||
15. | ALA1919952 | B | Inhibition of EAAT3-mediated D-aspartate transport at 100 uM | 2 | single protein format | Scientific Literature | |||
16. | ALA1016588 | B | Inhibition of glutamate-induced depolarization in human EAAT2 expressed in HEK293 cells by FMP assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
17. | ALA1016591 | B | Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
18. | ALA998473 | B | Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
19. | ALA998476 | B | Activity of human EAAT2 expressed in HEK293 cells up to 100 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA998479 | B | Activity at human EAAT2 expressed in HEK293 cells assessed as inhibition of Glu-induced fluorescent response by FLIPR membrane potential blue assay | Homo sapiens | 1 | cell-based format | Scientific Literature |