# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA677487 | B | Tested for 50 % inhibitory concentration against mouse soluble epoxide hydrolase (sEH) | 36 | single protein format | Scientific Literature | |||
2. | ALA677488 | B | Tested for 90 % inhibitory concentration against mouse soluble epoxide hydrolase (sEH) | 8 | single protein format | Scientific Literature | |||
3. | ALA677492 | B | Inhibition constant was determined against epoxide hydrolase | 2 | single protein format | Scientific Literature | |||
4. | ALA810461 | B | Inhibitory activity against murine soluble epoxide hydrolase | 9 | single protein format | Scientific Literature | |||
5. | ALA810462 | B | Inhibitory activity against murine soluble epoxide hydrolase; N/A = could not be determined because of above the highest concentration (500 uM) of inhibitor tested. | 1 | single protein format | Scientific Literature | |||
6. | ALA828060 | B | Inhibitory concentration against mouse soluble epoxide hydrolase (sEH) at 0.12 uM | Mus musculus | 32 | single protein format | Scientific Literature | ||
7. | ALA856477 | B | Inhibition of mouse recombinant soluble Epoxide hydrolase | Mus musculus | 40 | single protein format | Scientific Literature | ||
8. | ALA918223 | B | Inhibition of mouse soluble epoxide hydrolase by spectrometric based assay | Mus musculus | 22 | single protein format | Scientific Literature | ||
9. | ALA894934 | B | Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescent assay | Mus musculus | 4 | single protein format | Scientific Literature | ||
10. | ALA1671069 | B | Inhibition of mouse soluble epoxide hydrolase | Mus musculus | 1 | single protein format | Scientific Literature | ||
11. | ALA1053986 | B | Inhibition of mouse sEH | Mus musculus | 1 | single protein format | Scientific Literature | ||
12. | ALA1259738 | B | Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assay | Mus musculus | 52 | single protein format | Scientific Literature | ||
13. | ALA2174523 | B | Inhibition of mouse recombinant soluble epoxide hydrolase | Mus musculus | 1 | single protein format | Scientific Literature | ||
14. | ALA2437611 | B | Inhibition of mouse sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by fluorescence assay | Mus musculus | 35 | single protein format | Scientific Literature | ||
15. | ALA3887156 | B | FA: fluoresence competitive assay. | 15 | single protein format | BindingDB Database | |||
16. | ALA3887157 | B | t-DPPO: Trans-diphenylpropene oxide is used in a radiometric competitive assay. | 15 | single protein format | BindingDB Database | |||
17. | ALA3888170 | B | Fluorescent Based Assay: IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-(3-phenyl-oxyran-2-yl)methyl carbonate (CMNPC) was used as the fluorescent substrate. Human sEH (1 nM) or murine sEH (1 nM) was incubated with the inhibitor for 5 min in pH 7.0 Bis-Tris/HCl buffer (25 mM) containing 0.1 mg/mL of BSA at 30° C. prior to substrate introduction ([S]=5 μM). Activity was determined by monitoring the appearance of 6-methoxy-2-naphthaldehyde over 10 minutes by fluorescence detection with an excitation wavelength of 330 nm and an emission wavelength of 465 nm. | 51 | single protein format | BindingDB Database | |||
18. | ALA4124028 | B | Inhibition of recombinant mouse sEH expressed in baculovirus expression system using CMNPC as substrate preincubated for 5 mins followed by substrate addition measured for 10 mins by fluorescent based assay | Mus musculus | 10 | assay format | Scientific Literature | ||
19. | ALA4187643 | B | Inhibition of soluble epoxide in mouse brain microsomes using CMNPC substrate by fluorescence based assay | Mus musculus | 3 | microsome format | Scientific Literature | ||
20. | ALA4400283 | B | Inhibition of murine soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence based assay | Mus musculus | 15 | cell-based format | Scientific Literature |