# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3424159 | Binding | Inhibition of histamine H1 receptor (unknown origin) | Homo sapiens | 2 | ALA3421561 | single protein format | Scientific Literature | |
2. | ALA3579101 | Binding | Binding affinity to human histamine H1 receptor at 1 uM | Homo sapiens | 4 | ALA3576859 | single protein format | Scientific Literature | |
3. | ALA3584704 | Binding | Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in HEK cell membranes by radioligand binding assay | Homo sapiens | 1 | ALA3580564 | cell-based format | Scientific Literature | |
4. | ALA3592656 | Binding | Displacement of [3H]-pyrilamine from human cloned H1 receptor expressed in HEK293 cells at 1 uM by scintillation counting analysis | Homo sapiens | 4 | ALA3588770 | cell-based format | Scientific Literature | |
5. | ALA3592970 | Functional | Agonist activity at human recombinant H1 receptor expressed in HEK-293 cells assessed as intracellular Ca2+ release at 1 uM by fluorimetry | Homo sapiens | 2 | ALA3588770 | cell-based format | Scientific Literature | |
6. | ALA3592971 | Functional | Antagonist activity at human recombinant H1 receptor expressed in HEK-293 cells assessed as inhibition of histamine-induced intracellular Ca2+ release at 1 uM by fluorimetry | Homo sapiens | 2 | ALA3588770 | cell-based format | Scientific Literature | |
7. | ALA3602036 | Binding | Inhibition of human histamine H1 receptor at 10 uM relative to control | Homo sapiens | 1 | ALA3600314 | single protein format | Scientific Literature | |
8. | ALA3610159 | Binding | Binding affinity to histamine H1 receptor (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3608284 | single protein format | Scientific Literature | |
9. | ALA3610942 | Binding | Inhibition of recombinant human histamine H1 receptor | Homo sapiens | 2 | ALA3608218 | single protein format | Scientific Literature | |
10. | ALA3616209 | Binding | Binding affinity to human H1 receptor assessed as inhibition of control specific binding at 10 uM | Homo sapiens | 1 | ALA3612012 | single protein format | Scientific Literature | |
11. | ALA3616115 | Binding | Displacement of [3H]-pyrilamine from histamine H1 receptor (unknown origin) at 0.1 to 10 mM | Homo sapiens | 1 | ALA3611968 | single protein format | Scientific Literature | |
12. | ALA3624115 | Binding | Inhibition of human histamine H1 receptor at 10 uM relative to control | Homo sapiens | 2 | ALA3621160 | single protein format | Scientific Literature | |
13. | ALA3627351 | Binding | Binding affinity to histamine H1 receptor (unknown origin) | Homo sapiens | 1 | ALA3621061 | single protein format | Scientific Literature | |
14. | ALA3635151 | Binding | Binding affinity to histamine H1 receptor (unknown origin) at 3 uM by radioligand-binding assay | Homo sapiens | 1 | ALA3632469 | single protein format | Scientific Literature | |
15. | ALA3635325 | Functional | Agonist activity at histamine H1 receptor (unknown origin) expressed in CHO cells assessed as calcium mobilization at 3 uM | Homo sapiens | 1 | ALA3632469 | cell-based format | Scientific Literature | |
16. | ALA3635586 | Functional | Antagonist activity at histamine H1 receptor (unknown origin) expressed in CHO cells assessed as calcium mobilization at 3 uM | Homo sapiens | 1 | ALA3632469 | cell-based format | Scientific Literature | |
17. | ALA3636135 | Binding | Displacement of [3H]-Pyrilamine from recombinant human histamine H1 receptor at 10 uM after 1.5 hrs by Microbeta scintillation counting analysis relative to control | Homo sapiens | 1 | ALA3632459 | single protein format | Scientific Literature | |
18. | ALA3707498 | Binding | Binding Assay: Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors. | Homo sapiens | 7 | ALA3638417 | single protein format | BindingDB Database | |
19. | ALA3736710 | Binding | Displacement of [3H]Pyrilamine from human H1 Histamine receptors stably expressed in HEK cell membrane after 90 mins by scintillation counting method | Homo sapiens | 1 | ALA3734659 | cell-based format | Scientific Literature | |
20. | ALA3743547 | Functional | Agonist activity at human recombinant histamine H1 receptor expressed in CHO cells assessed as cAMP level at 10 uM after 4 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA3739407 | cell-based format | Scientific Literature |