# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3224752 | B | Inhibition of ACAT1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA3807133 | B | Inhibition of ACAT in human monocyte derived macrophages assessed as reduction in foam cell formation by measuring acetyl LDL-induced cholesterol ester accumulation at 30 uM after 24 hrs in presence of cholesteryl-[3H]oleate | Homo sapiens | 10 | single protein format | Scientific Literature | ||
3. | ALA4883185 | B | Thin Layer Chromatography (TLC) assay (human ACAT1) | Homo sapiens | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
4. | ALA5145932 | B | Inhibition of human ACAT1 in HepG2 cells assessed as inhibition of triglyceride synthesis at 100 nM incubated for 1 hrs followed by 13C-addition of 13C-oleic acid pre-complexed with fatty acid free BSA for 6 hrs by LC/MS/MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA5145934 | B | Inhibition of human ACAT1 in HepG2 cells assessed as inhibition of triglyceride synthesis at 300 nM incubated for 1 hrs followed by 13C-addition of 13C-oleic acid pre-complexed with fatty acid free BSA for 6 hrs by LC/MS/MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA5145935 | B | Inhibition of human ACAT1 in HepG2 cells assessed as inhibition of triglyceride synthesis at 1 uM incubated for 1 hrs followed by 13C-addition of 13C-oleic acid pre-complexed with fatty acid free BSA for 6 hrs by LC/MS/MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA5145936 | B | Inhibition of human ACAT1 in HepG2 cells assessed as inhibition of triglyceride synthesis incubated for 1 hrs followed by 13C-addition of 13C-oleic acid pre-complexed with fatty acid free BSA for 6 hrs by LC/MS/MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA5261192 | B | Inhibition of human ACAT1 at 100 uM | Homo sapiens | 1 | single protein format | Scientific Literature |