# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA858390 | B | Apparent binding constant for purified human kidney TPMT | Homo sapiens | 14 | tissue-based format | Scientific Literature | ||
2. | ALA814140 | B | Inhibition of purified human kidney thiopurine methyltransferase (TPMT) | 27 | single protein format | Scientific Literature | |||
3. | ALA3369580 | B | Binding affinity to thiopurine methyltransferase (unknown origin) by NMR analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA4416334 | A | Inhibition of human TPMT expressed in Escherichia coli assessed as reduction in SAH level at 10 uM using 6-mercaptopurine as substrate in presence of SAM incubated for 30 mins by LC-MS/MS analysis relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
5. | ALA4416341 | A | Inhibition of human TPMT expressed in Escherichia coli assessed as reduction in SAH level at 1 uM using 6-mercaptopurine as substrate in presence of SAM incubated for 30 mins by LC-MS/MS analysis relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
6. | ALA4416355 | A | Inhibition of human TPMT expressed in Escherichia coli assessed as reduction in SAH level using 6-mercaptopurine as substrate in presence of SAM incubated for 30 mins by LC-MS/MS analysis | Homo sapiens | 1 | assay format | Scientific Literature |