# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA678893 | B | Maximum percent potentiation against gamma-aminobutyric acid (GABA) A receptor, alpha 3 | Xenopus laevis | 24 | ALA1135642 | single protein format | Scientific Literature | |
2. | ALA678894 | B | Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 3 | Xenopus laevis | 23 | ALA1135642 | single protein format | Scientific Literature | |
3. | ALA678898 | B | Efficacy at Gamma-aminobutyric acid A receptor, alpha 3-ion channel relative to chlorodiazepoxide. | 19 | ALA1148234 | single protein format | Scientific Literature | ||
4. | ALA991891 | B | Binding affinity to GABAA alpha-3-beta-3-gamma-2 receptor | 4 | ALA1157475 | single protein format | Scientific Literature | ||
5. | ALA992826 | B | Activity at GABAA alpha-3-beta-3-gamma-2 receptor expressed in Xenopus oocytes assessed as potentiation of GABA-induced chloride current at 1 uM | 1 | ALA1157475 | cell-based format | Scientific Literature | ||
6. | ALA992834 | B | Activity at alpha-3-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current at 1 uM by voltage clamp assay | 1 | ALA1157475 | cell-based format | Scientific Literature | ||
7. | ALA999411 | B | Displacement of [3H]flunitrazepam from human recombinant GABAA alpha-3-beta-3-gamma-2 receptor expressed in HEK293 cells | Homo sapiens | 8 | ALA1141720 | cell-based format | Scientific Literature | |
8. | ALA960057 | B | Activity at GABAA alpha-3-beta-3-gamma-2 receptor expressed in oocytes assessed as stimulation of GABA-induced current at 1 uM relative to control | 3 | ALA1153371 | cell-based format | Scientific Literature | ||
9. | ALA2327260 | B | Positive allosteric modulation of GABAA alpha3 (unknown origin) relative to control | Homo sapiens | 3 | ALA2321869 | single protein format | Scientific Literature | |
10. | ALA2327956 | B | Positive allosteric modulation of GABAA alpha3 (unknown origin) | Homo sapiens | 4 | ALA2321869 | single protein format | Scientific Literature | |
11. | ALA4403719 | B | Binding affinity to GABA-A alpha3 (unknown origin) | Homo sapiens | 18 | ALA4402545 | single protein format | Scientific Literature | |
12. | ALA4403725 | B | Binding affinity to GABA-A alpha3 (unknown origin) assessed as increase in induced current relative to control | Homo sapiens | 15 | ALA4402545 | single protein format | Scientific Literature | |
13. | ALA4403772 | B | Binding affinity to GABA-A alpha3 (unknown origin) assessed as reduction in DMCM induced current relative to DMCM | Homo sapiens | 2 | ALA4402545 | single protein format | Scientific Literature | |
14. | ALA4403776 | B | Binding affinity to GABA-A alpha3 (unknown origin) assessed as reduction in DMCM induced current relative to control | Homo sapiens | 5 | ALA4402545 | single protein format | Scientific Literature | |
15. | ALA4415149 | B | Inhibition of GABAA receptor alpha3 (unknown origin) | Homo sapiens | 1 | ALA4414553 | single protein format | Scientific Literature | |
16. | ALA4701826 | A | Negative allosteric modulation of recombinant human GABA-A alpha3 expressed in HEK293 cells assessed as reduction in GABA-induced current at 1 uM relative to control | Homo sapiens | 21 | ALA4699487 | cell-based format | Scientific Literature | |
17. | ALA4701851 | A | Positive allosteric modulation of recombinant human GABA-A alpha3 expressed in HEK293 cells assessed as reduction in GABA-induced current at 1 uM relative to control | Homo sapiens | 10 | ALA4699487 | cell-based format | Scientific Literature | |
18. | ALA4837572 | B | Binding affinity to GABBA alpha3 (unknown origin) | Homo sapiens | 1 | ALA4837182 | single protein format | Scientific Literature | |
19. | ALA5235569 | B | Binding affinity to human recombinant GABAA alpha3 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting analysis | Homo sapiens | 21 | ALA5233266 | single protein format | Scientific Literature | |
20. | ALA5235575 | B | Inhibition of human recombinant GABAA alpha3 receptor | Homo sapiens | 1 | ALA5233266 | single protein format | Scientific Literature |