# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA950413 | B | Displacement of [3H]flumazenil in rat GABAA alpha-3-beta-3-gamma-2 receptor expressed in HEK293 cells | Rattus norvegicus | 3 | ALA1143446 | cell-based format | Scientific Literature | |
2. | ALA979092 | F | Agonist activity at rat recombinant GABAA alpha-3-beta-3-gamma-2 receptor expressed in HEK293 cells assessed as induction of current by whole cell patch-clamp technique | Rattus norvegicus | 1 | ALA1155944 | cell-based format | Scientific Literature | |
3. | ALA979934 | B | Intrinsic activity at recombinant rat GABAA alpha-3-beta-3-gamma-2 receptor expressed in HEK293 cells assessed as induction of current at 1 mM by whole-cell patch-clamp technique relative to GABA | Rattus norvegicus | 4 | ALA1155944 | cell-based format | Scientific Literature | |
4. | ALA970803 | F | Agonist activity at recombinant rat GABAA alpha-3-beta-3-gamma-2 receptor expressed in HEK293 cells assessed as potentiation of GABA-induced current at 1 mM by whole-cell patch-clamp technique | Rattus norvegicus | 1 | ALA1155944 | cell-based format | Scientific Literature | |
5. | ALA971725 | F | Agonist activity at rat recombinant GABAA alpha-3-beta-3-gamma-2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by whole cell patch-clamp technique | Rattus norvegicus | 1 | ALA1155944 | cell-based format | Scientific Literature | |
6. | ALA995050 | B | Inhibition of benzodiazepine binding site of rat GABAA alpha-3-beta-3-gamma-2 at 3.16 uM | Rattus norvegicus | 3 | ALA1144246 | single protein format | Scientific Literature | |
7. | ALA1111370 | F | Inverse agonist activity at rat GABA alpha-3-beta-3-gamma-2 receptor expressed in HEK293 cells by electrophysiology assay relative to GABA | Rattus norvegicus | 6 | ALA1154288 | cell-based format | Scientific Literature | |
8. | ALA2340572 | B | Agonist activity at rat GABAA alpha3beta3gamma2 receptor expressed in Xenopus oocytes assessed as stimulation of GABA-induced chloride current at 1 uM incubated 30 secs prior to GABA induction measured after 15 mins by two-electrode voltage clamp assay relative to control | Rattus norvegicus | 6 | ALA2331169 | cell-based format | Scientific Literature | |
9. | ALA2340573 | B | Agonist activity at rat GABAA alpha3beta3gamma2 receptor expressed in Xenopus oocytes assessed as stimulation of GABA-induced chloride current at 100 nM incubated 30 secs prior to GABA induction measured after 15 mins by two-electrode voltage clamp assay relative to control | Rattus norvegicus | 6 | ALA2331169 | cell-based format | Scientific Literature | |
10. | ALA3995202 | B | Displacement of [3H]RO15-1788 from recombinant rat GABAalpha3 receptor expressed in HEK293 cells after 1 hr | Rattus norvegicus | 2 | ALA3994587 | cell-based format | Scientific Literature |