| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA829541 | B | Inhibition of [3H]17-beta-estradiol binding to mouse ER alpha expressed in Escherichia coli | Mus musculus | 9 | assay format | Scientific Literature | ||
| 2. | ALA836291 | F | Bone mineral density of compound was determined in vivo against estrogen receptor alpha | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 3. | ALA836292 | F | Uterine weight assay of compound was determined in vivo against estrogen receptor alpha | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 4. | ALA836293 | F | Bone mineral density of ovx type raloxifene was determined in vivo against estrogen receptor alpha | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA836294 | F | Uterine weight assay of ovx type raloxifene was determined in vivo against estrogen receptor alpha | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA836295 | F | Bone mineral density of sham type raloxifene was determined in vivo against estrogen receptor alpha | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA836296 | F | Uterine weight assay of sham type raloxifene was determinedn in vivo against estrogen receptor alpha | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA946596 | B | Reversal of increase in DNA-binding activity of ERalpha in nuclear extracts of mouse MC3T3-E1 cells by electrophoretic mobility shift assays in presence of short interfering ER alpha-RNA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA946597 | B | Reversal of increase in DNA-binding activity of ERalpha in nuclear extracts of mouse MC3T3-E1 cells by electrophoretic mobility shift assays in presence of ICI-182780 | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA950713 | B | Increase in DNA-binding activity of ERalpha in nuclear extracts of mouse MC3T3-E1 cells by electrophoretic mobility shift assays | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA947605 | B | Reversal of increase in DNA-binding activity of ERalpha in nuclear extracts of mouse MC3T3-E1 cells transfected with dominant-negative mutant Src expression vector by electrophoretic mobility shift assays | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA947606 | B | Reversal of increase in DNA-binding activity of ERalpha in nuclear extracts of mouse MC3T3-E1 cells by electrophoretic mobility shift assays in presence of PP2 | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3253797 | B | Displacement of [6,7-3H]-17beta-estadiol from estrogen receptor in Tuck No. 1 mouse uterine cytosol at 1000 molar ratio of compound/radioligand incubated 15 mins prior to radioligand addition measured after 1 hr by liquid scintillation counting relative to control | Mus musculus | 7 | single protein format | Scientific Literature | ||
| 14. | ALA3253798 | B | Displacement of [6,7-3H]-17beta-estadiol from estrogen receptor in Tuck No. 1 mouse uterine cytosol at 3.16 molar ratio of compound/radioligand incubated 15 mins prior to radioligand addition measured after 1 hr by liquid scintillation counting relative to control | Mus musculus | 2 | single protein format | Scientific Literature | ||
| 15. | ALA3253799 | B | Displacement of [6,7-3H]-17beta-estadiol from estrogen receptor in Tuck No. 1 mouse uterine cytosol at 100 molar ratio of compound/radioligand incubated 15 mins prior to radioligand addition measured after 1 hr by liquid scintillation counting relative to control | Mus musculus | 2 | single protein format | Scientific Literature | ||
| 16. | ALA3253800 | B | Displacement of [6,7-3H]-17beta-estadiol from estrogen receptor in Tuck No. 1 mouse uterine cytosol at 10 molar ratio of compound/radioligand incubated 15 mins prior to radioligand addition measured after 1 hr by liquid scintillation counting relative to control | Mus musculus | 3 | single protein format | Scientific Literature | ||
| 17. | ALA3253801 | B | Displacement of [6,7-3H]-17beta-estadiol from estrogen receptor in Tuck No. 1 mouse uterine cytosol at 1 molar ratio of compound/radioligand incubated 15 mins prior to radioligand addition measured after 1 hr by liquid scintillation counting relative to control | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4018000 | B | Antagonist activity at estrogen receptor in mouse GT1-7 cells harboring beta-galactosidase reporter gene assessed as reduction in 17beta-estradiol induced response measured after 20 to 24 hrs by luciferase reporter gene assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4150135 | B | Induction of estrogen receptor-mediated AMPKalpha1 activation in mouse RAW264.7 cells at 20 uM in presence of estrogen receptor antagonist fulvestrant | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4150136 | B | Induction of estrogen receptor-mediated AMPKalpha1 activation in mouse RAW264.7 cells at 20 uM in presence of PKA inhibitor H89 | Mus musculus | 1 | cell-based format | Scientific Literature |
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