#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA1040724	F	Antagonist activity at mouse NR1/NR2B receptor D101A mutant expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current by two electrode voltage clamp method	Mus musculus	1		cell-based format	Scientific Literature
2.	ALA1941447	F	Antagonist activity at GluN2B/NMDA in FVB mouse CA1 pyramidal neurons assessed as reduction in NMDA-mediated inward current at 10 uM measured for 5 mins by whole-cell patch clamp assay in presence of glycine and tetrodotoxin	Mus musculus	2		cell-based format	Scientific Literature
3.	ALA2186395	F	Antagonist activity at NMDA receptor GluN2B subunit in FVB mouse CA1 pyramidal neurons assessed as decrease in EPSC amplitude at holding potential of -60 mV at 100 nM measured at 5 mins by patch clamp electrophysiological assay in presence of Mg2+ free ACSF containing CNQX, glycine, bicuculline relative to control	Mus musculus	1		cell-based format	Scientific Literature
4.	ALA2186396	F	Antagonist activity at NMDA receptor GluN2B subunit in FVB mouse CA1 pyramidal neurons assessed as decrease in EPSC amplitude at holding potential of -60 mV at 6 uM measured at 5 mins by patch clamp electrophysiological assay in presence of Mg2+ free ACSF containing CNQX, glycine, bicuculline relative to control	Mus musculus	1		cell-based format	Scientific Literature
5.	ALA2186397	B	Modulation of NMDA receptor GluN2B subunit in FVB mouse CA1 pyramidal neurons assessed as decrease in EPSC amplitude at holding potential of -60 mV at 10 uM measured at 5 mins by patch clamp electrophysiological assay in presence of Mg2+ free ACSF containing CNQX, glycine, bicuculline relative to control	Mus musculus	1		cell-based format	Scientific Literature
6.	ALA2186398	B	Modulation of NMDA receptor GluN2B subunit in FVB mouse CA1 pyramidal neurons assessed as increase in EPSC amplitude at holding potential of -60 mV at 10 uM measured at 5 mins by patch clamp electrophysiological assay in presence of Mg2+ free ACSF containing CNQX, glycine, bicuculline relative to control	Mus musculus	1		cell-based format	Scientific Literature
7.	ALA2186399	F	Antagonist activity at NMDA receptor GluN2B subunit in FVB mouse CA1 pyramidal neurons assessed as decrease in EPSC amplitude at holding potential of -60 mV at 50 uM measured at 5 mins by patch clamp electrophysiological assay in presence of Mg2+ free ACSF containing CNQX, glycine, bicuculline relative to control	Mus musculus	1		cell-based format	Scientific Literature
8.	ALA3108296	B	Antagonist activity at NMDA receptor GluN2B subunit in FVB mouse CA1 pyramidal neurons assessed as reversible reduction of excitatory post synaptic current amplitude at 50 nM at holding potential of -60 mV measured for 5 mins by patch clamp technique in presence of Mg2+free ACSF relative to control	Mus musculus	1		cell-based format	Scientific Literature
9.	ALA4058411	B	Antagonist activity at mouse NR2B expressed in Hek293 cells co-expressing mouse NR1 assessed as inhibition of glutamic acid/glycine-induced intracellular Ca2+ levels measured after 1 day post induction by Fluo-3/AM dye-based fluorescence assay	Mus musculus	27		cell-based format	Scientific Literature
10.	ALA4321003	B	Antagonist activity at mouse NR2B receptor expressed in HEK293 cells co-expressing NR1 subunit assessed as reduction in glutamic acid/glycine-induced calcium ion influx by fluorescence based assay	Mus musculus	32		cell-based format	Scientific Literature