| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA907931 | B | Activity at human NR2D expressed in Ltk- cells by patch clamp assay upto 30 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2427287 | B | Inhibition of NMDA GluN2D receptor (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA4149880 | B | Negative allosteric modulation of human GluN2D receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced channel current at 3 uM after 10 to 15 mins by two electrode voltage clamp based electrophysiology assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4308996 | B | Negative allosteric modulation of human GluN2D receptor expressed in HEK cells assessed as reduction in glycine/glutamate-induced intracellular calcium flux preincubated for 5 mins followed by glycine/glutamate addition by Fluo-4-AM dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4309001 | B | Negative allosteric modulation of human GluN2D receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel current at -40 mV holding potential by two electrode voltage clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4309007 | B | Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 7. | ALA4309008 | B | Positive allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4309015 | B | Positive allosteric modulation of EGFP-fused human GluN2D receptor expressed in HEK293T cells assessed as increase in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5058663 | B | GluN2D-containing NMDA receptor (Ca2+ influx) assay (EC50) | Homo sapiens | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 10. | ALA5058664 | B | GluN2D-containing NMDA receptor (Ca2+ influx) assay (potentiation) | Homo sapiens | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 11. | ALA5243891 | B | Positive allosteric modulator activity at GluN2D NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glutamate and glycine by Ca2+ influx assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5243892 | B | Positive allosteric modulator activity at GluN2D NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a assessed as maximum potentiation at 30 uM in the presence of L-glutamate and glycine by Ca2+ influx assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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