| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA805641 | F | Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cultured rat sympathetic neurons | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
| 2. | ALA1913012 | B | Inhibition of cloned rat SK2 channel expressed in human HEK293 cells by patch clamp assay in the presence of 1 uM intracellular Ca2+ | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4729854 | B | Inhibition of recombinant rat SK2 expressed in HEK293 cells assessed as decrease in intracellular calcium level at membrane potential -120 mV for 50 ms followed by 400 ms voltage ramp to 60 mV by whole cell patch clamp method | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4729856 | B | Inhibition of recombinant rat SK2 expressed in HEK293 cells at 10 nM and holding potential at 0 mV and ramp voltage from -100 to 100 mV by whole cell patch clamp method relative to control | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
| 5. | ALA4729858 | B | Inhibition of recombinant rat SK2 expressed in HEK293 cells at 100 nM and holding potential at 0 mV and ramp voltage from -100 to 100 mV by whole cell patch clamp method relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5041445 | B | Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology | Rattus norvegicus | 37 | cell-based format | Scientific Literature | ||
| 7. | ALA5041446 | B | Potentiation of rat KCa2.2a expressed in HEK293 cells at 0.01 to 100 uM with -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology relative to calcium | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA5041452 | B | Potentiation of rat KCa2.2a expressed in HEK293 cells assessed as increase in calcium response at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology | Rattus norvegicus | 2 | cell-based format | Scientific Literature |
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