# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA645471 | F | Efficacy relative to phenylephrine (PE) to constrict tissue containing the alpha-1A adrenergic receptor in rabbit urethra | Oryctolagus cuniculus | 29 | ALA1148329 | tissue-based format | Scientific Literature | |
2. | ALA645473 | F | Functional agonism of the compounds to constrict tissue containing the alpha-1A adrenergic receptor in rabbit urethra | Oryctolagus cuniculus | 29 | ALA1148329 | tissue-based format | Scientific Literature | |
3. | ALA645475 | F | Functional agonism of the compounds to constrict tissue containing the alpha-1A adrenergic receptor in rabbit urethra; NT = not tested | Oryctolagus cuniculus | 19 | ALA1148329 | tissue-based format | Scientific Literature | |
4. | ALA649046 | F | Antagonistic activity against alpha 1A/1L receptor was assessed in a rabbit bladder neck functional assay | Oryctolagus cuniculus | 61 | ALA1130120 | assay format | Scientific Literature | |
5. | ALA649047 | F | Antagonistic activity against alpha 1A/1L receptor in rabbit bladder neck functional assay; not tested | Oryctolagus cuniculus | 8 | ALA1130120 | assay format | Scientific Literature | |
6. | ALA979545 | F | Agonist activity at rabbit urethra adrenergic alpha1A receptor | Oryctolagus cuniculus | 1 | ALA1157194 | assay format | Scientific Literature | |
7. | ALA979548 | F | Antagonist activity at rabbit urethra adrenergic alpha1A receptor | Oryctolagus cuniculus | 1 | ALA1157194 | assay format | Scientific Literature | |
8. | ALA979549 | F | Antagonist activity at rabbit urethra adrenergic alpha1A receptor relative to phenylephrine | Oryctolagus cuniculus | 1 | ALA1157194 | assay format | Scientific Literature | |
9. | ALA2156100 | B | Ratio of BMY7378 KB to compound KB for rabbit aorta adrenergic alpha1A receptor assessed as inhibition of phenylephrine-induced constriction after 30 mins | Oryctolagus cuniculus | 2 | ALA2150896 | single protein format | Scientific Literature | |
10. | ALA2156106 | B | Binding affinity to rabbit aorta adrenergic alpha1A receptor assessed as inhibition of phenylephrine-induced constriction after 30 mins | Oryctolagus cuniculus | 18 | ALA2150896 | single protein format | Scientific Literature | |
11. | ALA3057222 | B | Agonist activity at alpha1A adrenoreceptor in Oryctolagus cuniculus (rabbit) urethra relative to phenylephrine | Oryctolagus cuniculus | 17 | ALA3046380 | single protein format | Scientific Literature | |
12. | ALA3056711 | B | Agonist activity at alpha1A adrenoreceptor in Oryctolagus cuniculus (rabbit) urethra | Oryctolagus cuniculus | 21 | ALA3046380 | single protein format | Scientific Literature |