| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2091591 | B | Inhibition of IkappaBalpha phosphorylation in human MDA-MB-231 cells at 5 to 20 uM after 3 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2091592 | B | Inhibition of IkappaBalpha phosphorylation in human MDA-MB-231 cells at 5 to 20 uM after 12 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA2091593 | B | Inhibition of IkappaBalpha phosphorylation in human MDA-MB-231 cells after 12 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA921575 | B | Inhibition of TNF-alpha-induced IkappaBalpha degradation in human Jurkat cells at 100 ug/mL after 2 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA946815 | B | Induction of human IkappaBalpha stabilization in OCI-Ly3 cells by green light emiting IkappaBalpha-fused luciferase reporter gene assay | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 6. | ALA946816 | B | Induction of human IkappaBalpha stabilization in OCI-Ly3 cells by green light emiting IkappaBalpha-fused luciferase reporter gene assay relative to control | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 7. | ALA945841 | B | Induction of human IkappaBalpha stabilization in OCI-Ly3 cells assessed as ratio of green light emiting IkappaBalpha-fused luciferase expression to red light emiting native luciferase expression | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 8. | ALA1943296 | B | Inhibition of IL1alpha-induced IkappaBalpha phosphorylation in human A549 cells at 10 to 100 uM incubated for 1 hr prior to IL1alpha challenge measured after 15 mins by Western blot analysis in the presence of proteasome inhibitor MG-132 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA1943297 | B | Inhibition of TNF-alpha-induced IkappaBalpha phosphorylation in human A549 cells at 10 to 100 uM incubated for 1 hr prior to TNFalpha challenge measured after 15 mins by Western blot analysis in the presence of proteasome inhibitor MG-132 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA1943298 | B | Inhibition of IL1alpha-induced IkappaBalpha phosphorylation in human A549 cells at 100 uM incubated for 1 hr prior IL1alpha challenge measured after 15 mins by Western blot analysis in the presence of proteasome inhibitor MG-132 | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA1943299 | B | Inhibition of TNF-alpha-induced IkappaBalpha phosphorylation in human A549 cells at 100 uM incubated for 1 hr prior TNFalpha challenge measured after 15 mins by Western blot analysis in the presence of proteasome inhibitor MG-132 | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA1958660 | B | Inhibition of TNF-alpha-induced IkappaBalpha degradation in human A549 cells at 4 to 8 uM treated 4 hrs before TNFalpha stimulation measured after 30 mins by Western blotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA1958916 | B | Inhibition of TNF-alpha-induced IkappaBalpha phosphorylation in human A549 cells at 4 to 8 uM treated 4 hrs before TNFalpha stimulation measured after 30 mins by Western blotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA966676 | B | Inhibition of LPS-induced IkappaBalpha phosphorylation in primary human monocytes upto 5 uM by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA1057324 | B | Inhibition of TNF-alpha-stimulated IkappaBalpha degradation in human A549 cells at 0.1 to 100 uM preincubated for 1 hr before TNFalpha challenge measured after 10 mins by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA1057325 | B | Inhibition of IL1-stimulated IkappaBalpha degradation in human A549 cells at 0.1 to 100 uM preincubated for 1 hr before IL1 challenge measured after 10 mins by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA2379364 | B | Inhibition of TNFalpha-induced IkappaB-alpha phosphorylation in human K562/ADR cells assessed as decrease in NKkappaB activity at 0.3 uM measured at 12 to 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA2412577 | B | Inhibition of TNFalpha-induced IkappaBalpha (unknown origin) degradation expressed in human HeLa cells at 50 uM pretreated 12.5 mins before TNFalpha addition measured after 30 mins by ELISA | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 19. | ALA2412579 | B | Inhibition of TNFalpha-induced IkappaBalpha (unknown origin) phosphorylation expressed in human HeLa cells pretreated 30 mins before TNFalpha addition measured up to 120 mins by ELISA in presence of proteasome inhibitor MG-132 | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 20. | ALA3269917 | B | Inhibition of IkappaB-alpha degradation in TNF-alpha-stimulated human Jurkat cells at 40 uM preincubated for 2 hrs followed by TNF-alpha challenge measured after 2 to 90 mins by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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