# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA860416 | Functional | Inhibition of IL1induced proteoglycan degradation in bovine cartilage, 3 day incubation at 10 ug/mL | Bos taurus | 1 | ALA1147767 | assay format | Scientific Literature | |
2. | ALA1913360 | Binding | Inhibition of aggrecanase 1 in bovine cartilage explant assessed as inhibition of IL1-stimulated proteoglycan degradation at 10 ug/ml | Bos taurus | 3 | ALA1909576 | single protein format | Scientific Literature | |
3. | ALA980696 | Binding | Inhibition of IL1-induced aggrecanase activity in bovine cartilage explant assessed as release of degraded extracellular matrix aggrecan | Bos taurus | 4 | ALA1138597 | single protein format | Scientific Literature | |
4. | ALA980697 | Binding | Inhibition of IL1-induced aggrecanase activity in bovine cartilage explant assessed as inhibition of proteoglycan degradation at 10 ug/ml after 3 days | Bos taurus | 4 | ALA1138597 | single protein format | Scientific Literature | |
5. | ALA2352571 | Binding | Ex vivo inhibition of ADAMTS-4-mediated aggrecan degradation in IL-1-stimulated bovine cartilage explant at 30 uM | Bos taurus | 1 | ALA2346648 | single protein format | Scientific Literature |