# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA659810 | Binding | Inhibition of recombinant rat Cathepsin B | Rattus norvegicus | 14 | ALA1136415 | single protein format | Scientific Literature | |
2. | ALA659811 | Binding | Second order rate constant for the inactivation of cathepsin B at pH 6.5 was reported | 2 | ALA1128502 | single protein format | Scientific Literature | ||
3. | ALA659812 | Binding | Second order rate constant for the inactivation of cathepsin B at pH 6.0 was reported; No time dependent inhibition observed | 1 | ALA1128502 | single protein format | Scientific Literature | ||
4. | ALA923083 | Binding | Inhibition of rat liver lysosomal cathepsin B | Rattus norvegicus | 10 | ALA1140679 | assay format | Scientific Literature | |
5. | ALA1228686 | Binding | Binding affinity to cathepsin B in crude rat liver homogenates using [125I]DCG-04 based competition protein labeling by SDS-PAGE method | Rattus norvegicus | 6 | ALA1221168 | tissue-based format | Scientific Literature | |
6. | ALA1228691 | Binding | Binding affinity to cathepsin B in crude rat liver homogenates using [125I]DCG-04 based competition protein labeling up to 50 uM by SDS-PAGE method | Rattus norvegicus | 1 | ALA1221168 | tissue-based format | Scientific Literature | |
7. | ALA3999664 | Binding | Inhibition of rat cathepsin B at 100 uM using cbz-phe-Arg-amidomethylcoumarin as substrate measured for 15 mins by fluorescence assay relative to control | Rattus norvegicus | 3 | ALA3997824 | single protein format | Scientific Literature | |
8. | ALA3999665 | Binding | Inhibition of rat cathepsin B at 1 uM using cbz-phe-Arg-amidomethylcoumarin as substrate measured for 15 mins by fluorescence assay relative to control | Rattus norvegicus | 1 | ALA3997824 | single protein format | Scientific Literature | |
9. | ALA3999666 | Binding | Inhibition of rat cathepsin B at 100 uM using cbz-phe-Arg-amidomethylcoumarin as substrate preincubated for 5 mins followed by substrate addition measured for 15 mins by fluorescence assay relative to control | Rattus norvegicus | 3 | ALA3997824 | single protein format | Scientific Literature | |
10. | ALA3999667 | Binding | Inhibition of rat cathepsin B at 1 uM using cbz-phe-Arg-amidomethylcoumarin as substrate preincubated for 5 mins followed by substrate addition measured for 15 mins by fluorescence assay relative to control | Rattus norvegicus | 1 | ALA3997824 | single protein format | Scientific Literature | |
11. | ALA4668020 | ADME | Inhibition of rat cathepsin B at 100 uM using Z-FR-AMC as substrate measured after 15 mins without preincubation by microplate reader based assay relative to control | Rattus norvegicus | 2 | ALA4665666 | single protein format | Scientific Literature | |
12. | ALA4668021 | ADME | Inhibition of rat cathepsin B at 100 uM using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by microplate reader based assay relative to control | Rattus norvegicus | 2 | ALA4665666 | single protein format | Scientific Literature | |
13. | ALA4668022 | ADME | Inhibition of rat cathepsin B at 50 uM using Z-FR-AMC as substrate measured after 15 mins without preincubation by microplate reader based assay relative to control | Rattus norvegicus | 1 | ALA4665666 | single protein format | Scientific Literature | |
14. | ALA4668023 | ADME | Inhibition of rat cathepsin B at 50 uM using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by microplate reader based assay relative to control | Rattus norvegicus | 1 | ALA4665666 | single protein format | Scientific Literature | |
15. | ALA4668024 | ADME | Inhibition of rat cathepsin B at 1 uM using Z-FR-AMC as substrate measured after 15 mins without preincubation by microplate reader based assay relative to control | Rattus norvegicus | 1 | ALA4665666 | single protein format | Scientific Literature | |
16. | ALA4668025 | ADME | Inhibition of rat cathepsin B at 1 uM using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by microplate reader based assay relative to control | Rattus norvegicus | 1 | ALA4665666 | single protein format | Scientific Literature |