| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA879748 | B | Concentration for half maximal activation of metabotropic glutamate mGluR7 in rat | 5 | assay format | Scientific Literature | |||
| 2. | ALA712463 | B | Effect on Metabotropic glutamate receptor 7 | 4 | single protein format | Scientific Literature | |||
| 3. | ALA712464 | F | Metabotropic glutamate receptor 7 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cells | 6 | cell-based format | Scientific Literature | |||
| 4. | ALA712465 | F | Metabotropic glutamate receptor 7 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cells; Not tested | 5 | cell-based format | Scientific Literature | |||
| 5. | ALA712466 | F | Metabotropic glutamate receptor 7 antagonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cells | 1 | cell-based format | Scientific Literature | |||
| 6. | ALA839722 | B | Binding affinity towards metabotropic glutamate receptor 7 of rat expressed in CHO cells was determined by using [3H]MGS-0008 | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA912664 | F | Activity at rat mGluR7 receptor measured as intracellular calcium concentration in HEK293 cells | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA1925098 | B | Positive allosteric modulator activity at rat mGlu7 receptor at 10 uM by thallium flux assay relative to glutamate | Rattus norvegicus | 3 | single protein format | Scientific Literature | ||
| 9. | ALA1925099 | F | Agonist activity at rat mGlu7 receptor at 10 uM by thallium flux assay relative to L-AP4 | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 10. | ALA1925106 | F | Antagonist activity at rat mGlu7 receptor at 10 uM by thallium flux assay | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
| 11. | ALA1925178 | B | Positive allosteric modulator activity at rat mGlu7 receptor at 10 uM by thallium flux assay | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 12. | ALA1925179 | B | Positive allosteric modulator activity at rat mGlu7 receptor assessed as potentiation of glutamate-induced thallium flux at 10 uM relative to (-)-PHCCC | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 13. | ALA896249 | F | Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate production | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA1069931 | F | Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Rattus norvegicus | 21 | cell-based format | Scientific Literature | ||
| 15. | ALA1110796 | F | Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular calcium level after 1 hr by fluorescence microplate reader | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
| 16. | ALA1110797 | F | Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular inositol phosphate accumulation after 1 hr by scintillation counting | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA1678455 | B | Positive allosteric modulation in rat mGluR7 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced response at 10 uM | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA1696003 | B | Potentiation of rat mGluR7 receptor assessed as fold shift in glutamate concentration response curve at 10 uM relative to control | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 19. | ALA1738666 | F | PUBCHEM_BIOASSAY: Modulation of the Metabotropic Glutamate Receptor mGluR4: Selectivity at mGluR7. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2437, AID2807] | Rattus norvegicus | 3 | assay format | PubChem BioAssays | ||
| 20. | ALA2183981 | B | Positive allosteric modulation activity at rat mGlu7R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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