| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA757347 | F | Effective agonist concentration to the human Orexin receptor type 2 was determined using the Xlfit program | 79 | assay format | Scientific Literature | |||
| 2. | ALA757348 | B | Inhibitory concentration against human orexin-2 receptor (hOX2R) | 29 | single protein format | Scientific Literature | |||
| 3. | ALA757349 | B | Compound was evaluated for its binding affinity towards Orexin receptor type 2 | 1 | single protein format | Scientific Literature | |||
| 4. | ALA840218 | B | Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 5. | ALA835462 | F | Antagonistic activity towards intracellular calcium levels in cells expressing Orexin receptor type 2 | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA857325 | F | Agonist activity against human orexin 2 receptor; EC50; nM | Homo sapiens | 61 | assay format | Scientific Literature | ||
| 7. | ALA1833030 | F | Antagonist activity at recombinant human OX2R expressed in CHO cells by FLIPR calcium based functional assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 8. | ALA1833036 | B | Displacement of [3H]almorexant from recombinant human OX2R expressed in CHO cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA1833038 | F | Agonist activity at recombinant human OX2R expressed in CHO cells at 1 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA932891 | B | Displacement of [3H](S)-N-(2-(1H-pyrrol-1-yl)phenyl)-1-(2-(1-methyl-1H-benzo[d]imidazol-2-ylthio)acetyl)pyrrolidine-2-carboxamide from human OX2R expressed in CHO cells | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 11. | ALA932892 | F | Antagonist activity at human OX2R expressed in CHOK1 cells assessed as effect on calcium mobilization | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 12. | ALA2034510 | F | Antagonist activity at OX2 receptor expressed in CHO cells assessed as inhibition of OXA-stimulated intracellular calcium mobilization after 30 mins by FLIPR assay | 30 | cell-based format | Scientific Literature | |||
| 13. | ALA1913449 | F | Antagonist activity at OX2R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium mobilization by FLIPR assay | 8 | cell-based format | Scientific Literature | |||
| 14. | ALA1914018 | F | Antagonist activity at human OX2R expressed in CHO cells assessed intracellular calcium mobilization by FLIPR assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 15. | ALA1964010 | F | PUBCHEM_BIOASSAY: Counterscreen assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1): Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based dose response assay for antagonists of the orexin 2 receptor (OX2R; HCRTR2), run by assay provider. (Class of assay: confirmatory) | 213 | cell-based format | PubChem BioAssays | |||
| 16. | ALA1963974 | F | PUBCHEM_BIOASSAY: Counterscreen assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1): Fluorescence-based cell-based dose response assay for antagonists of the orexin 2 receptor (OX2R; HCRTR2), run by assay provider. (Class of assay: confirmatory) | 213 | cell-based format | PubChem BioAssays | |||
| 17. | ALA1007893 | F | Antagonist activity at human OX2 receptor expressed in CHO cells assessed as inhibition of receptor-mediated calcium response by FLIPR | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA1007898 | F | Antagonist activity at human OX2 receptor | Homo sapiens | 29 | assay format | Scientific Literature | ||
| 19. | ALA1007903 | B | Binding affinity to OX2 receptor | 18 | single protein format | Scientific Literature | |||
| 20. | ALA1007909 | B | Inhibition of OX2 receptor | 37 | single protein format | Scientific Literature |
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