| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3631241 | Binding | Inhibition of human placental microsomal 17beta HSD2 using unlabeled- and labelled [2,4,6,7-3H]-E2 as substrate incubated for 20 mins by HPLC analysis | Homo sapiens | 37 | ALA3627664 | assay format | Scientific Literature | |
| 2. | ALA3631249 | Binding | Inhibition of human placental microsomal 17beta HSD2 at 1 uM using unlabeled- and labelled [2,4,6,7-3H]-E2 as substrate incubated for 20 mins by HPLC analysis | Homo sapiens | 1 | ALA3627664 | assay format | Scientific Literature | |
| 3. | ALA3707914 | Binding | Radioactivity Assay: The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-587 (1995): Sam, K. M. et al., Drug Des Discov., 15:157-180 (1997)). The radioactivity is determined by means of scintillation measurement. | Homo sapiens | 14 | ALA3638998 | assay format | BindingDB Database | |
| 4. | ALA3744292 | Binding | Inhibition of 17beta-HSD2 in human placental microsomal fraction using E2/NAD+ as substrate/cofactor after 20 mins by HPLC analysis | Homo sapiens | 5 | ALA3739412 | assay format | Scientific Literature | |
| 5. | ALA3744294 | Binding | Inhibition of 17beta-HSD2 in human placental microsomal fraction using E2/NAD+ as substrate/cofactor at 1 uM after 20 mins by HPLC analysis | Homo sapiens | 20 | ALA3739412 | assay format | Scientific Literature | |
| 6. | ALA615155 | Binding | Inhibitory activity against human placenta 17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD type 2) | 1 | ALA1149930 | assay format | Scientific Literature | ||
| 7. | ALA615156 | Binding | Inhibitory constant against human placenta 17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD type 2) | 1 | ALA1149930 | assay format | Scientific Literature | ||
| 8. | ALA884518 | Binding | Inhibitory activity against human placenta 17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD type 2) | 1 | ALA1149930 | assay format | Scientific Literature | ||
| 9. | ALA829588 | Binding | Inhibitory concentration against 17 beta hydroxysteroid dehydrogenase type 2 (type II 17-beta-HSD II) | 62 | ALA1139623 | single protein format | Scientific Literature | ||
| 10. | ALA836265 | Binding | Inhibitory activity against 17 beta hydroxysteroid dehydrogenase type 2 at 10 uM in MDA-MB-231 cells | Homo sapiens | 3 | ALA1143588 | cell-based format | Scientific Literature | |
| 11. | ALA856121 | Binding | Inhibitory activity at 10 uM against 17-beta-hydroxysteroid dehydrogenase type 2 in MDAMB-231 human breast cancer cells using 2 nM [3H]estradiol | Homo sapiens | 1 | ALA1141073 | cell-based format | Scientific Literature | |
| 12. | ALA856122 | Binding | Inhibitory activity at 10 uM against 17-beta-hydroxysteroid dehydrogenase type 2 in MDAMB-231 human breast cancer cells using 2 nM [3H]estradiol | Homo sapiens | 32 | ALA1141073 | cell-based format | Scientific Literature | |
| 13. | ALA856126 | Binding | Inhibitory activity at 10 uM against 17-beta-hydroxysteroid dehydrogenase type 2 in MDAMB-231 human breast cancer cells using 2 nM [3H]estradiol; b is not determined | Homo sapiens | 4 | ALA1141073 | cell-based format | Scientific Literature | |
| 14. | ALA881958 | Binding | Inhibitory activity at 10 uM against 17-beta-hydroxysteroid dehydrogenase type 2 in MDAMB-231 human breast cancer cells using 2 nM [3H]estradiol for 3 hr; c is not determined | Homo sapiens | 1 | ALA1141073 | cell-based format | Scientific Literature | |
| 15. | ALA864129 | Functional | Inhibition of 17-beta HSD2 in MDA-MB231cells at 10 uM | Homo sapiens | 78 | ALA1149452 | assay format | Scientific Literature | |
| 16. | ALA870159 | Binding | Inhibition of human recombinant 17-beta-HSD2 expressed in HEK293 cells | Homo sapiens | 5 | ALA1148531 | cell-based format | Scientific Literature | |
| 17. | ALA870160 | Binding | Inhibition of human recombinant 17betaHSD2 expressed in HEK293 cells at 30 uM | Homo sapiens | 2 | ALA1148531 | cell-based format | Scientific Literature | |
| 18. | ALA908034 | Binding | Inhibition of human recombinant 17beta-HSD2 | Homo sapiens | 34 | ALA1149363 | single protein format | Scientific Literature | |
| 19. | ALA908035 | Functional | Inhibition of estradiol to estrone conversion in MG63 cells | Homo sapiens | 5 | ALA1149363 | cell-based format | Scientific Literature | |
| 20. | ALA1068443 | Binding | Inhibition of 17beta-HSD2 by human cell based assay | 3 | ALA1153171 | cell-based format | Scientific Literature |
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