| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA749961 | F | In vitro antagonist potency in transactivation assay in NIH3T3 cells expressing glucocorticoid receptor | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA749965 | F | In vitro antagonist potency in transactivation assay in NIH3T3 cells expressing glucocorticoid receptor | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA750124 | F | In vitro agonist potency in transactivation assay in NIH3T3 cells expressing glucocorticoid receptor; NE=no effect | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA749312 | F | In vitro agonist potency in transactivation assay in NIH3T3 cells expressing glucocorticoid receptor | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA829188 | B | Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cells | Mus musculus | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA829726 | B | GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 mice | Mus musculus | 15 | cell-based format | Scientific Literature | ||
| 7. | ALA829032 | B | Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cells; nd=not determined | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 8. | ALA830789 | B | Percent absolute inhibition of LPS-induced tumor necrosis factor alpha release in mice at 3 mg/kg dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA830532 | B | Percent absolute inhibition of LPS-induced tumor necrosis factor alpha release in mice at 30 mg/kg dose | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA834028 | B | Percent inhibition of LPS-induced tumor necrosis factor alpha release in mice relative to prednisolone at 3 mg/kg dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA834033 | B | Percent inhibition of LPS-induced tumor necrosis factor alpha release in mice relative to prednisolone at 30 mg/kg dose | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA836158 | B | Percent absolute inhibition of LPS-induced tumor necrosis factor alpha release in mice at 30 mg/kg dose; ne = Not effective | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA932413 | B | Activity at glucocorticoid receptor in mouse ATT20 cells assessed as repression of POMC gene expression after 24 hrs by RT-PCR | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA2353363 | B | Induction of glucocorticoid receptor nuclear translocation in mouse C2C12 cells at 1 x 10'-5 to 1.69 x 10'-10 M by chemiluminescence assay relative to control | Mus musculus | 20 | cell-based format | Scientific Literature | ||
| 15. | ALA3281630 | B | Binding affinity to glucocorticoid receptor in soluble fraction of mouse L929 cells assessed as dissociation half life | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3281632 | B | Displacement of 1 x 10'-8 M of [1,2,3-3H]-triamcinolone acetonide from glucocorticoid receptor in soluble fraction of mouse L929 cells after 20 hrs | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA3281634 | B | Displacement of 2 x 10'-8 M of [1,2,3-3H]-triamcinolone acetonide from glucocorticoid receptor in soluble fraction of mouse L929 cells after 20 hrs | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA3281635 | B | Binding affinity to glucocorticoid receptor in soluble fraction of mouse L929 cells at 10'-7 M at 0 degC | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3281640 | B | Displacement of [1,2,3-3H]-triamcinolone acetonide from glucocorticoid receptor in soluble fraction of mouse L929 cells at 10'-7 M preincubated for 4 hrs followed by [3H]-triamcinolone acetonide addition measured after 18 hrs by double reciprocal plot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3281641 | B | Displacement of [1,2,3-3H]-triamcinolone acetonide from glucocorticoid receptor in soluble fraction of mouse L929 cells at 10'-6 M preincubated for 4 hrs followed by [3H]-triamcinolone acetonide addition measured after 18 hrs by double reciprocal plot analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!