# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA699591 | F | Agonistic activity against human opioid Kappa receptor transfected into Chinese hamster ovary (CHO) cells using [3H]U-69593 as radioligand | 3 | cell-based format | Scientific Literature | |||
2. | ALA699592 | F | Antagonistic activity against human opioid Kappa receptor transfected into Chinese hamster ovary (CHO) cells using [3H]U-69593 as radioligand | 1 | cell-based format | Scientific Literature | |||
3. | ALA699593 | B | Binding affinity towards human opioid Kappa receptor transfected into Chinese hamster ovary (CHO) cells using [3H]U-69593 as radioligand. | 5 | cell-based format | Scientific Literature | |||
4. | ALA699594 | F | Agonistic activity against human opioid Kappa receptor transfected into Chinese hamster ovary (CHO) cells using [3H]U-69593 as radioligand | 5 | cell-based format | Scientific Literature | |||
5. | ALA884407 | F | Agonistic activity against human opioid Kappa receptor transfected into Chinese hamster ovary (CHO) cells using [3H]U-69593 as radioligand | 1 | cell-based format | Scientific Literature | |||
6. | ALA699596 | B | In vitro binding property against kappa opioid receptor | 71 | single protein format | Scientific Literature | |||
7. | ALA700230 | B | Binding affinity towards opioid kappa receptor using [3H]U-69593 as radioligand | 3 | single protein format | Scientific Literature | |||
8. | ALA700231 | B | Binding affinity towards opioid kappa receptor using [3H]U-69593 as radioligand | 4 | single protein format | Scientific Literature | |||
9. | ALA700232 | B | Binding affinity towards opioid kappa receptor using [3H]U-69593 as radioligand; Not available | 1 | single protein format | Scientific Literature | |||
10. | ALA700233 | B | Binding affinity towards opioid kappa receptor using [3H]U69,593 as radioligand; not active | 1 | single protein format | Scientific Literature | |||
11. | ALA700235 | F | Opioid receptor kappa agonist potency in vitro using rabbit vas deferens (LVD) preparation; Not Tested | Oryctolagus cuniculus | 1 | tissue-based format | Scientific Literature | ||
12. | ALA700236 | F | Opioid receptor kappa agonist potency in vitro using rabbit vas deferens(LVD) preparation | Oryctolagus cuniculus | 1 | assay format | Scientific Literature | ||
13. | ALA700238 | B | Displacement of [3H]naloxone from human kappa opioid receptor | Homo sapiens | 11 | single protein format | Scientific Literature | ||
14. | ALA700239 | B | Affinity for human kappa opioid receptor was determined from competition binding curves using [3H]-naloxone; ND means not determined. | 4 | single protein format | Scientific Literature | |||
15. | ALA740126 | F | Antinociceptive activity at kappa opioid receptor antagonist norbinaltorphimine (norBNI) at the dose of 12 umol/kg (sc) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
16. | ALA750337 | F | Effective dose for agonistic activity towards human kappa opioid receptor from membranes of HEK293 cells was determined by radiolabeled [35S]GTP-gamma-S, assay | 3 | cell-based format | Scientific Literature | |||
17. | ALA750338 | F | Functional activity in HEK293 cells overexpressing the human kappa opioid receptor was determined using a radiolabeled [35S]GTP-gamma-S, assay | 1 | cell-based format | Scientific Literature | |||
18. | ALA750339 | F | Incorporation of [35S]GTP-gamma-S, into CHO membranes expressing human Opioid receptor kappa 1 | Homo sapiens | 12 | assay format | Scientific Literature | ||
19. | ALA750340 | B | Compound was tested for maximum stimulation of opioid receptor kappa 1 by GTP-gamma [35S]- binding assay | 6 | single protein format | Scientific Literature | |||
20. | ALA750341 | F | Percent maximal stimulation of [35S]GTP-gamma-S, binding to recombinant human Opioid receptor kappa 1 expressed in CHO cells | 2 | cell-based format | Scientific Literature |