# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA664617 | Binding | Percent inhibition towards dopamine D2 receptor | 1 | ALA1134028 | single protein format | Scientific Literature | ||
2. | ALA664618 | Binding | Percent inhibition towards dopamine D2 receptor at 100 nM concentration | 1 | ALA1134028 | single protein format | Scientific Literature | ||
3. | ALA858328 | Binding | Compound was evaluated for binding activity against [3H]haloperidol as radioligand for Dopamine receptor D2 | 1 | ALA1123428 | single protein format | Scientific Literature | ||
4. | ALA669953 | Binding | Binding affinity against dopamine D2 receptor | 16 | ALA1127331 | single protein format | Scientific Literature | ||
5. | ALA669954 | Binding | In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound; NT means not tested | 1 | ALA1123617 | tissue-based format | Scientific Literature | ||
6. | ALA669955 | Binding | Percent decrease in Dopamine receptor D2 binding using spiperone | Rattus norvegicus | 4 | ALA1133101 | single protein format | Scientific Literature | |
7. | ALA668189 | Binding | Displacement of [3H]spiroperidol from dopamine receptor D2 binding sites of rat striatal membranes; inactive | Rattus norvegicus | 9 | ALA1125521 | cell membrane format | Scientific Literature | |
8. | ALA668190 | Binding | Binding affinity at dopamine receptor D2 from rat by spiropiperidone displacement. | 17 | ALA1134337 | single protein format | Scientific Literature | ||
9. | ALA669509 | Binding | Affinity of compound towards dopamine-D2 receptor was determined in presence of [3H](-)-sulpiride radioligand | 1 | ALA1125016 | single protein format | Scientific Literature | ||
10. | ALA672647 | Binding | Affinity constant of compound was evaluated in rat striatum tissue preparation. | 1 | ALA1124222 | tissue-based format | Scientific Literature | ||
11. | ALA672648 | Functional | Dopamine D2 agonistic activity (2 mg/kg) as percent change in prolactin level in reserpinized rats | Rattus norvegicus | 8 | ALA1124588 | organism-based format | Scientific Literature | |
12. | ALA672649 | Functional | Dopamine receptor D2 agonistic activity (1 mg/kg) is assessed from percent change in prolactine level in reserpinized rats;p<0.001 | 1 | ALA1124588 | organism-based format | Scientific Literature | ||
13. | ALA672650 | Binding | Inhibitory activity against Dopamine receptor D2 in rat corpus striatum using [3H]apomorphine as radioligand | 1 | ALA1124655 | tissue-based format | Scientific Literature | ||
14. | ALA672651 | Binding | Inhibitory activity against dopamine receptor D2 in rat corpus striatum using [3H]apomorphine as radioligand | 3 | ALA1124655 | tissue-based format | Scientific Literature | ||
15. | ALA672803 | Functional | Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | 34 | ALA1125832 | cell-based format | Scientific Literature | ||
16. | ALA672804 | Functional | Formation of cAMP on Dopamine receptor D2 in vitro in rat intermediate lobe | Rattus norvegicus | 5 | ALA1125128 | assay format | Scientific Literature | |
17. | ALA672805 | Binding | In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assay | 2 | ALA1148372 | cell-based format | Scientific Literature | ||
18. | ALA672806 | Functional | In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assay | 1 | ALA1148372 | cell-based format | Scientific Literature | ||
19. | ALA672807 | Binding | In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assay | 1 | ALA1148372 | cell-based format | Scientific Literature | ||
20. | ALA672808 | Functional | In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assay; Not an agonist up to 10 uM | 1 | ALA1148372 | cell-based format | Scientific Literature |