| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA880346 | B | Binding constant (K) against Tat/TAR using 1:1 quinolone/Mg2+ complex done at 25 degree C with pH 7.5 | Human immunodeficiency virus 1 | 3 | single protein format | Scientific Literature | ||
| 2. | ALA881698 | B | In vitro binding affinity towards Tat/TAR to determine interaction between TAR RNA and Tat peptide at room temperature using fluorescence spectrophotometer | Human immunodeficiency virus 1 | 4 | single protein format | Scientific Literature | ||
| 3. | ALA881699 | B | In vitro binding affinity towards Tat/TAR to determine interaction between TAR RNA and Tat peptide at room temperature using fluorescence spectrophotometer; nb denotes no binding | Human immunodeficiency virus 1 | 2 | single protein format | Scientific Literature | ||
| 4. | ALA881700 | B | In vitro binding affinity towards Tat/TAR to determine interaction between TAR RNA and Tat peptide at room temperature using fluorescence spectrophotometer; mb denotes multiple binding | Human immunodeficiency virus 1 | 1 | single protein format | Scientific Literature | ||
| 5. | ALA917012 | B | Inhibition of Tat-mediated transcription of viral promoter in 293 T cells transfected with HIV1 tat by luciferase reporter gene assay | Human immunodeficiency virus 1 | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA978137 | B | Inhibition of HIV1 Tat-mediated LTR promoter transactivation in Tat/GFP plasmid expressed in Jurkat cells assessed as GFP gene expression by FACS analysis | Human immunodeficiency virus 1 | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA1100196 | B | Inhibition of HIV1 TAT transfected to human HeLa cells assessed as decrease in luminescence after 48 hrs by duel luciferase reporter gene assay | Human immunodeficiency virus 1 | 9 | cell-based format | Scientific Literature | ||
| 8. | ALA3362911 | B | Inhibition of HIV1 Tat-mediated transactivation of HIV1 long terminal repeat in human HeLa cells after 24 hrs by LTR driven luciferase reporter assay | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA3562022 | F | PubChem BioAssay. An HIV-1 Tat-TAR Fluorescence Polarization (FP) Counter Screen to evaluate Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G. (Class of assay: confirmatory) | 989 | assay format | PubChem BioAssays | |||
| 10. | ALA4142857 | B | Inhibition of HIV1 Tat-mediated LTR transcriptional activity expressed in HEK293 cells after 48 hrs by dual-luciferase reporter gene assay | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4397086 | B | Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as LTR-driven gene expression incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay | Human immunodeficiency virus 1 | 102 | cell-based format | Scientific Literature | ||
| 12. | ALA4397087 | B | Activation of Tat-mediated HIV1 transcription in HEK293-FlpIn.RV cells harboring LTR driven CBG reporter co-expressing CMV driven CBR reporter assessed as LTR-driven gene expression incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4397097 | B | Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as maximum LTR activity at 20 uM incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay relative to control | Human immunodeficiency virus 1 | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4397098 | B | Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as maximum LTR activity at 5 uM incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay relative to control | Human immunodeficiency virus 1 | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4397099 | B | Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as maximum LTR activity at 1.3 uM incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay relative to control | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4397100 | B | Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as maximum LTR activity at 0.31 uM incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay relative to control | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4397101 | B | Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as maximum LTR activity at 2.5 uM incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay relative to control | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA4397102 | B | Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as maximum LTR activity at 0.63 uM incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay relative to control | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4397103 | B | Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as maximum LTR activity at 0.005 uM incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay relative to control | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4397104 | B | Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as maximum LTR activity at 0.2 uM incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay relative to control | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature |
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