| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA654501 | B | Tested for ability to block the CD4-gp120 interaction measured by binding of [125I]sCD4 to gp120 | 1 | single protein format | Scientific Literature | |||
| 2. | ALA655875 | B | Tested for inhibition of HIV gp120-CD4 interaction in an ELISA based binding assay using recombinant CD4-gp120 | 1 | single protein format | Scientific Literature | |||
| 3. | ALA655876 | B | Tested for inhibition of binding of soluble recombinant CD4-gp120 using ELISA assay | 3 | single protein format | Scientific Literature | |||
| 4. | ALA655877 | B | Tested for inhibition of binding of soluble recombinant CD4-gp120 using ELISA assay; IA is Inactive | 10 | single protein format | Scientific Literature | |||
| 5. | ALA655878 | B | Tested in an HIV viral syncytium assay for inhibition of binding of recombinant CD4-gp120 | 1 | single protein format | Scientific Literature | |||
| 6. | ALA655879 | B | Tested for inhibition of HIV CD4-gp120 interaction in an ELISA based binding assay using recombinant gp120 and soluble CD4 up to a concentration of 350 uM; No inhibition | 2 | single protein format | Scientific Literature | |||
| 7. | ALA655880 | B | Tested for inhibition of HIV CD4-gp120 interaction in an ELISA based binding assay using recombinant gp120 and soluble CD4 up to a concentration of 550 uM; No inhibition | 1 | single protein format | Scientific Literature | |||
| 8. | ALA655881 | B | Tested for rate constant of binding to inhibit soluble recombinant CD4-gp120; value ranges form 4-20 uM | 1 | single protein format | Scientific Literature | |||
| 9. | ALA692010 | B | Binding affinity towards HIV glycoprotein gp120 | 1 | single protein format | Scientific Literature | |||
| 10. | ALA822507 | F | In vitro for the cytotoxicity against the gp41 core domain(HIV-I). | 16 | assay format | Scientific Literature | |||
| 11. | ALA1245741 | B | Inhibition of HIV1 HXB2 gp120-mediated viral infusion into HEK293 cells after 24 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA1245742 | B | Inhibition of HIV1 HXB2 gp120-mediated viral infusion into HEK293 cells after 24 hrs by luciferase reporter gene assay relative to control | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA1245745 | B | Inhibition of HIV1 HXB2 gp120-mediated viral infusion into HEK293 cells after 24 hrs by luciferase reporter gene assay in presence of 45 mg/ml human serum albumin | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA1245746 | B | Ratio of IC50 for inhibition of HIV1 HXB2 gp120-mediated viral infusion into HEK293 cells in presence of 45 mg/ml human serum albumin to IC50 for inhibition of HIV1 HXB2 gp120-mediated viral infusion into HEK293 cells in absence of 45 mg/ml human serum albumin | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA1245747 | B | Inhibition of HIV1 HXB2 gp120-mediated viral infusion into HEK293 cells after 24 hrs by luciferase reporter gene assay in presence of 1 mg/ml alpha-acid glycoprotein | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA1245748 | B | Ratio of IC50 for inhibition of HIV1 HXB2 gp120-mediated viral infusion into HEK293 cells in presence of 1 mg/ml alpha-acid glycoprotein to IC50 for inhibition of HIV1 HXB2 gp120-mediated viral infusion into HEK293 cells in absence of 1 mg/ml alpha-acid glycoprotein | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA1245749 | B | Inhibition of HIV1 HXB2 gp120-mediated viral infusion into HEK293 cells after 24 hrs by luciferase reporter gene assay in presence of alpha-acid glycoprotein and human serum albumin | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA1245750 | B | Ratio of IC50 for inhibition of HIV1 HXB2 gp120-mediated viral infusion into HEK293 cells in presence of alpha-acid glycoprotein and HSA to IC50 for inhibition of HIV1 HXB2 gp120-mediated viral infusion into HEK293 cells in absence of alpha-acid glycoprotein and HSA | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA1646734 | B | Inhibition of HIV1 YU2 gp120 D368A mutant binding to CD4 expressing Cf2Th-CD4/CCR5 cells assessed as inhibition of viral infection after 48 hrs | Human immunodeficiency virus type 1 (isolate YU2) | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA1646735 | B | Inhibition of HIV1 YU2 gp120 S375A mutant binding to CD4 expressing Cf2Th-CD4/CCR5 cells assessed as inhibition of viral infection after 48 hrs | Human immunodeficiency virus type 1 (isolate YU2) | 3 | cell-based format | Scientific Literature |
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