| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA699460 | B | Inhibitory activity against Isoleucyl-tRNA synthetase | Escherichia coli | 18 | single protein format | Scientific Literature | ||
| 2. | ALA832651 | B | Inhibitory concentration against Escherichia coli Ile-tRNA synthetase | Escherichia coli | 4 | single protein format | Scientific Literature | ||
| 3. | ALA1918864 | B | Competitive inhibition of Escherichia coli Isoleucyl-tRNA synthetase | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 4. | ALA3257517 | B | Inhibition of Ile-tRNA synthetase in Escherichia coli NP29 assessed as tRNA-Ile level at 230 uM at 30 degC after 30 mins (Rvb = 40%) | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 5. | ALA3257954 | B | Inhibition of Ile-tRNA synthetase in rel+ Escherichia coli B assessed as tRNA-Ile level at 4.6 uM at 37 degC after 30 mins in absence of casamino acid supplement in tris-glucose minimal media (Rvb = 40%) | Escherichia coli B | 1 | assay format | Scientific Literature | ||
| 6. | ALA3257956 | B | Inhibition of Ile-tRNA synthetase in rel+ Escherichia coli B assessed as tRNA-Ile level at 23 uM at 37 degC after 30 mins in absence of casamino acid supplement in tris-glucose minimal media (Rvb = 40%) | Escherichia coli B | 1 | assay format | Scientific Literature | ||
| 7. | ALA3257959 | B | Inhibition of Ile-tRNA synthetase in rel+ Escherichia coli B assessed as tRNA-Ile level at 230 uM at 37 degC after 30 mins in absence of casamino acid supplement in tris-glucose minimal media (Rvb = 40%) | Escherichia coli B | 1 | assay format | Scientific Literature | ||
| 8. | ALA3254831 | B | Inhibition of Ile-tRNA synthetase in rel+ Escherichia coli B assessed as tRNA-Ile level at 9.2 uM at 37 degC after 30 mins in absence of casamino acid supplement in tris-glucose minimal media (Rvb = 40%) | Escherichia coli B | 1 | assay format | Scientific Literature | ||
| 9. | ALA3255261 | B | Inhibition of Ile-tRNA synthetase in rel+ Escherichia coli B assessed as tRNA-Ile level at 230 uM at 37 degC after 30 mins in presence of casamino acid supplement in tris-glucose minimal media (Rvb = 50%) | Escherichia coli B | 1 | assay format | Scientific Literature | ||
| 10. | ALA3271206 | B | Inhibition of Isoleucine-tRNA synthetase in wild type Escherichia coli S30 cell extract assessed as inhibition of [C14]isoleucine incorporation in tRNA under in vitro aminoacylation conditions at 3.13 uM by liquid scintillation counting | Escherichia coli | 7 | assay format | Scientific Literature | ||
| 11. | ALA3830141 | B | Inhibition of Escherichia coli isoleucyl-tRNA synthetase assessed as decrease in [3H]isoleucyl-tRNA generation | Escherichia coli | 2 | assay format | Scientific Literature | ||
| 12. | ALA4197601 | B | Inhibition of Isoleucyl-tRNA synthetase in Escherichia coli K-12 BW28357 S30 extract assessed as reduction in tRNA aminoacylation at 2.5 uM preincubated for 5 mins followed by Escherichia coli tRNA and 14C-labeled isoleucine addition measured after 5 mins by liquid scintillation counting method relative to control | Escherichia coli K-12 | 2 | single protein format | Scientific Literature | ||
| 13. | ALA4197607 | B | Inhibition of Escherichia coli BL21(DE3) Isoleucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichia coli tRNA and 14C-labeled isoleucine followed by ATP addition by liquid scintillation counting method | Escherichia coli BL21(DE3) | 2 | single protein format | Scientific Literature | ||
| 14. | ALA4394779 | B | Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assay | Escherichia coli BL21(DE3) | 3 | single protein format | Scientific Literature | ||
| 15. | ALA4394781 | B | Inhibition of ileRS in Escherichia coli NCIB 8743 S30 extract assessed as aminoacylation at 250 nM incubated for 5 mins in presence of 14C-labeled isoleucine by liquid scintillation counting method relative to control | Escherichia coli | 4 | single protein format | Scientific Literature | ||
| 16. | ALA4394786 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing RimI incubated for 5 to 60 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature | ||
| 17. | ALA4394789 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing SUMO incubated for 5 to 60 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature | ||
| 18. | ALA4394792 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing RimL incubated for 5 to 60 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 6 | single protein format | Scientific Literature | ||
| 19. | ALA4394794 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing YhhY incubated for 5 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 3 | single protein format | Scientific Literature | ||
| 20. | ALA4394795 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing YhhY incubated for 60 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 3 | single protein format | Scientific Literature |
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