| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2183452 | B | Binding affinity to Escherichia coli FtsZ at 40 uM by fluorescence anisotropy BoGTPgammaS competition assay | Escherichia coli | 1 | ALA2176974 | single protein format | Scientific Literature | |
| 2. | ALA2183455 | B | Binding affinity to Escherichia coli FtsZ by fluorescence anisotropy BoGTPgammaS competition assay | Escherichia coli | 1 | ALA2176974 | single protein format | Scientific Literature | |
| 3. | ALA2183457 | B | Stimulation of Escherichia coli FtsZ assembly at 20 ug/mL by transmission electron microscopy | Escherichia coli | 1 | ALA2176974 | single protein format | Scientific Literature | |
| 4. | ALA2183814 | B | Stimulation of Escherichia coli FtsZ self-polymerization at 40 ug/mL by microtiter plate-based light scattering assay | Escherichia coli | 3 | ALA2176974 | single protein format | Scientific Literature | |
| 5. | ALA2187135 | B | Stimulation of Escherichia coli FtsZ self-polymerization by microtiter plate-based light scattering assay | Escherichia coli | 1 | ALA2176974 | single protein format | Scientific Literature | |
| 6. | ALA2187142 | B | Binding affinity to Escherichia coli FtsZ at 25 degC by fluorescence anisotropy assay | Escherichia coli | 3 | ALA2176974 | single protein format | Scientific Literature | |
| 7. | ALA3418981 | B | Inhibition of Escherichia coli FtsZ GTPase activity | Escherichia coli | 6 | ALA3414448 | single protein format | Scientific Literature | |
| 8. | ALA3418982 | B | Inhibition of Escherichia coli FtsZ polymerization | Escherichia coli | 2 | ALA3414448 | single protein format | Scientific Literature | |
| 9. | ALA3419201 | B | Inhibition of Escherichia coli FtsZ assessed as reduction in substrate KM value | Escherichia coli | 1 | ALA3414448 | single protein format | Scientific Literature | |
| 10. | ALA3419202 | B | Binding affinity to Escherichia coli FtsZ by fluorescence anisotrophy | Escherichia coli | 1 | ALA3414448 | single protein format | Scientific Literature | |
| 11. | ALA3419203 | B | Inhibition of FtsZ in Escherichia coli assessed as Z-ring containing cells level at 4 and 8 ug/ml (Rvb = 88%) | Escherichia coli | 1 | ALA3414448 | assay format | Scientific Literature | |
| 12. | ALA3419208 | B | Inhibition of Escherichia coli FtsZ | Escherichia coli | 1 | ALA3414448 | single protein format | Scientific Literature | |
| 13. | ALA3419210 | B | Inhibition of Escherichia coli FtsZ assembly | Escherichia coli | 2 | ALA3414448 | single protein format | Scientific Literature | |
| 14. | ALA3424283 | B | Inhibition of Escherichia coli ATCC 25922 recombinant N-His6-tagged FtsZ polymerization expressed in Escherichia coli BL21(DE3) by light scattering assay | Escherichia coli | 3 | ALA3421607 | assay format | Scientific Literature | |
| 15. | ALA3424284 | B | Inhibition of Escherichia coli ATCC 25922 recombinant N-His6-tagged FtsZ polymerization expressed in Escherichia coli BL21(DE3) incubated for 15 mins prior to GTP addition measured after 390 mins by malachite green staining-based GTPase assay | Escherichia coli | 3 | ALA3421607 | assay format | Scientific Literature | |
| 16. | ALA3429345 | B | Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay | Escherichia coli | 30 | ALA3425501 | single protein format | Scientific Literature | |
| 17. | ALA3429349 | B | Competitive inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay in presence of 10 to 1250 uM GTP | Escherichia coli | 1 | ALA3425501 | single protein format | Scientific Literature | |
| 18. | ALA3865870 | B | Inhibition of recombinant Escherichia coli K12 FtsZ assembly by light-scattering assay | Escherichia coli K-12 | 1 | ALA3865781 | single protein format | Scientific Literature | |
| 19. | ALA3865871 | B | Inhibition of recombinant Escherichia coli K12 FtsZ GTPase activity by malachite green sodium molybdate assay | Escherichia coli K-12 | 1 | ALA3865781 | single protein format | Scientific Literature | |
| 20. | ALA3887391 | B | GTPase Activity Assay: GTPase assays were performed in 50 mM MES, pH 6.5, 50 mM KCl, 5 mM MgCl2 in the presence of 2 uM FtsZ in the presence of varying concentrations of compound 1. Solutions were incubated at room temperature for 5 min, followed by addition of 0.25 mM GTP. At the end of a 20-min incubation period, enzyme activity was quenched by addition of 50 uL Malachite Green solution and the wells read at A625 on an absorbance plate reader. | 2 | ALA3886301 | single protein format | BindingDB Database |
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