# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA681936 | B | Ability to displace [3H]flunitrazepam ([3H]-FNP) binding to mouse brain after intraperitoneal administration at a dose 10 umol/kg | Mus musculus | 1 | ALA1124397 | tissue-based format | Scientific Literature | |
2. | ALA681937 | B | Ability to displace [3H]Flunitrazepam ([3H]FNP) binding to mouse brain after intraperitoneal administration at a dose 100 umol/kg | Mus musculus | 1 | ALA1124397 | tissue-based format | Scientific Literature | |
3. | ALA681938 | B | Ability to displace [3H]flunitrazepam ([3H]-FNP) binding to mouse brain after intraperitoneal administration at a dose 320 umol/kg | Mus musculus | 1 | ALA1124397 | tissue-based format | Scientific Literature | |
4. | ALA682048 | B | Ability to displace [3H]flunitrazepam ([3H]-FNP) binding to mouse brain after intraperitoneal administration at a dose 1000 umol/kg | Mus musculus | 1 | ALA1124397 | tissue-based format | Scientific Literature | |
5. | ALA682052 | B | Tested for % inactivation of the displacement of [3H]mazindol from GABA receptor (52% at 25 uM) | Rattus norvegicus | 1 | ALA1127070 | single protein format | Scientific Literature | |
6. | ALA681143 | B | Inhibitory effect was measured for [3H]GABA-uptake from rat synaptosomal membrane | Rattus norvegicus | 1 | ALA1123200 | assay format | Scientific Literature | |
7. | ALA680231 | B | Tested for in vitro inhibition of the displacement of [3H]mazindol from GABA receptor | Rattus norvegicus | 2 | ALA1127070 | single protein format | Scientific Literature | |
8. | ALA713900 | F | Ability to displace [3H]flunitrazepam ([3H]-FNP) binding to mouse brain after intraperitoneal administration at a dose 320 umol/kg | Mus musculus | 9 | ALA1124397 | organism-based format | Scientific Literature | |
9. | ALA717883 | F | Ability to displace [3H]flunitrazepam ([3H]-FNP) binding to mouse brain after intraperitoneal administration at a dose 320 umol/kg | Mus musculus | 22 | ALA1124397 | organism-based format | Scientific Literature | |
10. | ALA736345 | F | Administered at a dose 320 umol/kg intraperitoneally before [3H]Flunitrazepam ([3H]-FNP) in mouse brain expressed as percent of control | Mus musculus | 20 | ALA1124397 | tissue-based format | Scientific Literature | |
11. | ALA954626 | B | Displacement of [3H]flumazenil from rat GABA-A alpha-2-beta-2-gamma-2 receptor expressed in HEK293 cells | Rattus norvegicus | 19 | ALA1136986 | cell-based format | Scientific Literature | |
12. | ALA954627 | B | Displacement of [3H]flumazenil from rat GABA-A alpha-2-beta-2-gamma-2 receptor expressed in HEK293 cells at 10 uM | Rattus norvegicus | 1 | ALA1136986 | cell-based format | Scientific Literature | |
13. | ALA954631 | F | Agonist activity at rat GABA-A alpha-2-beta-2-gamma-2 receptor expressed in HEK293 cells assessed as increase in 36Cl- influx | Rattus norvegicus | 4 | ALA1136986 | cell-based format | Scientific Literature | |
14. | ALA3995201 | B | Displacement of [3H]RO15-1788 from recombinant rat GABAalpha2 receptor expressed in HEK293 cells after 1 hr | Rattus norvegicus | 3 | ALA3994587 | cell-based format | Scientific Literature | |
15. | ALA5235580 | B | Displacement of [3H]-flumazenil from rat recombinant alpha2 GABAA receptor assessed as inhibition constant in presence of zolpidem | Rattus norvegicus | 1 | ALA5233266 | single protein format | Scientific Literature |