# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA642517 | B | Compound was tested for the competitive inhibition of acetylcholinesterase (AChE) | 6 | ALA1124669 | single protein format | Scientific Literature | ||
2. | ALA642518 | B | In vitro inhibitory activity against acetylcholinesterase | 1 | ALA1126157 | single protein format | Scientific Literature | ||
3. | ALA642519 | B | IC50 (hBuChE/hAChE) ratio of the compound | 5 | ALA1134774 | single protein format | Scientific Literature | ||
4. | ALA642520 | B | Inhibitory activity against Acetylcholinesterase at 10 min (48 mM conc) | 1 | ALA1125311 | single protein format | Scientific Literature | ||
5. | ALA642521 | B | Compound was evaluated for reversible inhibition of hydrolysis acetylcholine by acetylcholinesterase and represented as KI(com) | 4 | ALA1123043 | single protein format | Scientific Literature | ||
6. | ALA642409 | B | Compound was evaluated for reversible inhibition of hydrolysis acetylcholine by acetylcholinesterase and represented as KI(competitive) | 9 | ALA1123043 | single protein format | Scientific Literature | ||
7. | ALA642410 | B | Compound was evaluated for reversible inhibition of hydrolysis acetylcholine by acetylcholinesterase and represented as KI(noncompetitive) | 7 | ALA1123043 | single protein format | Scientific Literature | ||
8. | ALA642411 | B | Compound was evaluated for reversible inhibition of hydrolysis of acetylcholine by acetylcholinesterase and represented as KI(competitive) | 1 | ALA1123043 | single protein format | Scientific Literature | ||
9. | ALA642412 | B | Binding affinity towards Acetylcholinesterase | 1 | ALA1128453 | single protein format | Scientific Literature | ||
10. | ALA642413 | B | Inhibition constant determined against Acetylcholinesterase (AChE) receptor. | 1 | ALA1131149 | single protein format | Scientific Literature | ||
11. | ALA643078 | B | Compound was evaluated for reversible inhibition of hydrolysis acetylcholine by acetylcholinesterase and represented as Km(app) apparent binding constant | 10 | ALA1123043 | single protein format | Scientific Literature | ||
12. | ALA644288 | B | The second order inhibition rate constant for the compound was measured against acetylcholinesterase | 1 | ALA1127410 | single protein format | Scientific Literature | ||
13. | ALA644289 | B | The second order inhibition rate constant for the compound was measured against acetylcholinesterase; NI-No inhibition after 30 min of incubation of enzyme with inhibitor | 1 | ALA1127410 | single protein format | Scientific Literature | ||
14. | ALA644290 | B | The second order inhibition rate constant for the compound was measured against acetylcholinesterase; NI-No inhibition after 30 min of incubation of enzyme with inhibitor | 1 | ALA1127410 | single protein format | Scientific Literature | ||
15. | ALA644291 | F | Effect of pretreatment on the Acetylcholinesterase (AChE) activity when exposed to glutamate | 2 | ALA1132802 | assay format | Scientific Literature | ||
16. | ALA638604 | B | Compound was tested for the percentage of maximum reactivation for GD-inhibited human erythrocyte acetylcholinesterase (AChE) | Homo sapiens | 1 | ALA1124669 | single protein format | Scientific Literature | |
17. | ALA638605 | F | Tested for inhibition of AChE-induced Abeta aggregation in the peripheral sites of the human enzyme at a concentration of 100 uM | Homo sapiens | 2 | ALA1145004 | assay format | Scientific Literature | |
18. | ALA642747 | B | Inhibition of choline acetyltransferase (ChAT) activity | 2 | ALA1124246 | single protein format | Scientific Literature | ||
19. | ALA660249 | B | Enzyme inhibition dissociation constant for choline acetyl transferase (ChAcT) was determined | Bos taurus | 1 | ALA1126723 | single protein format | Scientific Literature | |
20. | ALA660250 | B | Rate of acetylation of 13.0+/-1.1 umol compound by 1 g of choline acetyltransferase (ChAc) by incubating for 10 minutes at 37 degrees Centigrade | 6 | ALA1122667 | single protein format | Scientific Literature |