| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA752246 | F | Antagonistic activity against NR1A/2C receptor in frog oocytes | frog | 22 | cell-based format | Scientific Literature | ||
| 2. | ALA907930 | B | Activity at human NR2C expressed in Ltk- cells by patch clamp assay upto 30 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4149879 | B | Negative allosteric modulation of human GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced channel current at 3 uM after 10 to 15 mins by two electrode voltage clamp based electrophysiology assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4309000 | B | Negative allosteric modulation of human GluN2C receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel current at -40 mV holding potential by two electrode voltage clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4309006 | B | Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 6. | ALA4309011 | B | Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4309014 | B | Positive allosteric modulation of EGFP-fused human GluN2C receptor expressed in HEK293T cells assessed as increase in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5058661 | B | GluN2C-containing NMDA receptor (Ca2+ influx) assay (EC50) | Homo sapiens | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 9. | ALA5058662 | B | GluN2C-containing NMDA receptor (Ca2+ influx) assay (potentiation) | Homo sapiens | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 10. | ALA5243889 | B | Positive allosteric modulator activity at GluN2C NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glutamate and glycine by Ca2+ influx assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5243890 | B | Positive allosteric modulator activity at GluN2C NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a assessed as maximum potentiation at 30 uM in the presence of L-glutamate and glycine by Ca2+ influx assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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