| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA686851 | F | Inhibition of [beta-Ala]NKA(4-10)-induced contraction of isolated guinea pig trachea | Cavia porcellus | 18 | tissue-based format | Scientific Literature | ||
| 2. | ALA745326 | B | Evaluated for the binding affinity against NK2 receptor | Cavia porcellus | 1 | single protein format | Scientific Literature | ||
| 3. | ALA744937 | B | Inhibitory activity against Neurokinin 2 (NK2) receptor from guinea pig ileum | Cavia porcellus | 27 | tissue-based format | Scientific Literature | ||
| 4. | ALA744938 | F | Antagonist activity against Neurokinin 2 (NK2) receptor from guinea pig ileum at a concentration of 1 ug/mL | Cavia porcellus | 43 | tissue-based format | Scientific Literature | ||
| 5. | ALA744939 | F | Compound was evaluated for NK-2 receptor antagonistic activity in the guinea pig trachea | Cavia porcellus | 1 | assay format | Scientific Literature | ||
| 6. | ALA751784 | F | Inhibitory activity against Tachykinin receptor 2 evaluated as beta-ala-NKA (410) induced bronchospasm inhibition after a oral dose of 10 mpk in guinea pig | Cavia porcellus | 1 | assay format | Scientific Literature | ||
| 7. | ALA882026 | F | In vivo efficacy expressed as dose ratio for bronchoconstriction induced by BANK as agonist for NK2 receptor in anesthetized guinea pig at 30 uM/kg dose by oral administration | Cavia porcellus | 2 | organism-based format | Scientific Literature | ||
| 8. | ALA751785 | F | The compound was tested in vivo for antagonism against neurokinin NK2 receptor in isolated guinea pig trachea. | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA814792 | B | Base dissociation constant measured against Tachykinin receptor 2 | Cavia porcellus | 1 | single protein format | Scientific Literature | ||
| 10. | ALA814793 | B | Effective dose concentration required for In vivo binding affinity towards Tachykinin receptor 2 (NK2) receptor after oral administration in presence of agonist ASMSP in guinea pig pulmonary tissue in lung plasma extravation assay | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA814794 | F | Effective dose of concentration required for In vivo potency (ED50 ratio for Tachykinin receptor 2 (NK2) in presence and absence of antagonist) in guinea pig PMM after intravenous administration at a dose 10 uM/Kg | Cavia porcellus | 5 | organism-based format | Scientific Literature | ||
| 12. | ALA814795 | F | Effective dose of concentration required for In vivo potency (ED50 ratio for Tachykinin receptor 2 (NK2) in presence and absence of antagonist) in guinea pig PMM after oral administration at a dose 30 uM/Kg | Cavia porcellus | 5 | organism-based format | Scientific Literature | ||
| 13. | ALA814796 | F | Effective dose of concentration required for In vivo potency (ED50 ratio for Tachykinin receptor 2 in presence and absence of antagonist) in guinea pig PMM after intravenous administration at a dose 10 uM/Kg | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA878869 | B | In vivo binding affinity towards Tachykinin receptor 2 (NK2) after oral administration in presence of agonist ASMSP in guinea pig pulmonary tissue in lung plasma extravation assay | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA814797 | B | In vivo binding affinity towards Tachykinin receptor 2 (NK2) receptor after oral administration in presence of agonist ASMSP in guinea pig pulmonary tissue in lung plasma extravation assay | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA814798 | F | Antagonist Activity of compound (100 nM) at Tachykinin receptor 2 at guinea pig trachea in the presence of P-Ala8-NKA[4-IO] as agonist | Cavia porcellus | 1 | assay format | Scientific Literature | ||
| 17. | ALA814799 | F | Antagonist Activity of compound (10 nM) at Tachykinin receptor 2 at guinea pig trachea in the presence of P-Ala8-NKA[4-IO] as agonist | Cavia porcellus | 1 | assay format | Scientific Literature | ||
| 18. | ALA816671 | F | Antagonist Activity of compound (30 nM) at Tachykinin receptor 2 at guinea pig trachea in the presence of P-Ala8-NKA[4-IO] as agonist | Cavia porcellus | 1 | assay format | Scientific Literature | ||
| 19. | ALA816672 | B | The compound was evaluated in vitro for its ability to displace [3H]SP from Tachykinin receptor 2 of male guinea pig lung membrane | Cavia porcellus | 8 | tissue-based format | Scientific Literature | ||
| 20. | ALA816673 | F | Effective dose of concentration required for In vivo potency (ED50 ratio for Tachykinin receptor 2 (NK2) in presence and absence of antagonist) in guinea pig PMM after oral administration at a dose 30 uM/Kg; ND is Not determined | Cavia porcellus | 1 | organism-based format | Scientific Literature |
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