# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA676601 | B | Displacement of radioligand from human Estrogen receptor beta, percent inhibition at 10 uM | Homo sapiens | 1 | ALA1135457 | single protein format | Scientific Literature | |
2. | ALA676602 | B | Displacement of radioligand from human Estrogen receptor beta, percent inhibition at 10 uM | Homo sapiens | 5 | ALA1135457 | single protein format | Scientific Literature | |
3. | ALA676603 | B | Displacement of radioligand from human ER beta | Homo sapiens | 3 | ALA1135457 | single protein format | Scientific Literature | |
4. | ALA677950 | B | Binding of [3H]E2 alkyl ester to human estrogen receptor beta ligand binding domain expressed in Escherichia coli | Homo sapiens | 6 | ALA1145034 | assay format | Scientific Literature | |
5. | ALA677951 | B | In vitro displacement of 0.5 nM [3H]E2 from human Estrogen receptor beta at 10 uM | Homo sapiens | 4 | ALA1136750 | single protein format | Scientific Literature | |
6. | ALA677952 | B | Affinity for human estrogen receptor beta | Homo sapiens | 2 | ALA1136473 | single protein format | Scientific Literature | |
7. | ALA677953 | F | Agonist effect on transcriptional activation of T47D cells expressing human estrogen receptor beta | Homo sapiens | 1 | ALA1135674 | cell-based format | Scientific Literature | |
8. | ALA677954 | B | Transcriptional potency (EC50) at Human estrogen receptor Beta | 22 | ALA1134292 | single protein format | Scientific Literature | ||
9. | ALA677955 | F | Antagonist effect on transcriptional activation in HEC-1 cells expressing Estrogen receptor beta at 10e-6 M against 10e-9 M estradiol | Homo sapiens | 5 | ALA1145083 | cell-based format | Scientific Literature | |
10. | ALA677956 | F | Agonist effect on transcriptional activation in HEC-1 cells expressing Estrogen receptor beta at 10e-8 M | Homo sapiens | 5 | ALA1145083 | cell-based format | Scientific Literature | |
11. | ALA677957 | F | Agonist effect on transcriptional activation of T47D cells expressing human estrogen receptor beta; Inactive at 10e-4 M | Homo sapiens | 5 | ALA1135674 | cell-based format | Scientific Literature | |
12. | ALA677958 | F | Agonist effect on transcriptional activation of T47D cells expressing human estrogen receptor beta; Inactive at 10e-4 M | Homo sapiens | 1 | ALA1135674 | cell-based format | Scientific Literature | |
13. | ALA677959 | B | In vitro inhibition of 1 nM 17-beta-estradiol induced transcriptional activation in T47D cells expressing estrogen receptor beta; Inactive at 10e-4 M | Homo sapiens | 1 | ALA1135674 | cell-based format | Scientific Literature | |
14. | ALA678127 | B | Percent of maximal transcriptional activation in T47D cells expressing estrogen receptor beta compared to 17-beta-estradiol; Inactive at 10e-4 M | Homo sapiens | 1 | ALA1135674 | cell-based format | Scientific Literature | |
15. | ALA678128 | B | Binding affinity for Human Estrogen receptor-beta | Homo sapiens | 9 | ALA1136557 | single protein format | Scientific Literature | |
16. | ALA678129 | B | In vitro inhibition of 1 nM 17-beta-estradiol induced transcriptional activation in T47D cells expressing estrogen receptor beta | Homo sapiens | 7 | ALA1135674 | cell-based format | Scientific Literature | |
17. | ALA678130 | B | Inhibitory concentration against estrogen receptor 2 using estrogen response element (ERE) assay. | 25 | ALA1145829 | single protein format | Scientific Literature | ||
18. | ALA678131 | B | Inhibitory concentration against estrogen receptor 2 using radioligand binding assay. | 26 | ALA1145829 | single protein format | Scientific Literature | ||
19. | ALA678132 | B | Minimum effective concentration required to inhibit Estrogen receptor 2 (ER beta); Not detected | 28 | ALA1145088 | single protein format | Scientific Literature | ||
20. | ALA678133 | B | Percent maximal inhibition of 1 nM 17-beta-estradiol induced transcriptional activation in T47D cells expressing estrogen receptor beta | Homo sapiens | 7 | ALA1135674 | cell-based format | Scientific Literature |