| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA809058 | B | Binding affinity against Sodium/glucose co-transporter of isolated renal brush border membranes. | Homo sapiens | 19 | assay format | Scientific Literature | ||
| 2. | ALA834934 | F | In vitro inhibition of Na-dependent [14C]AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 3. | ALA863284 | B | Inhibitory activity towards human SGLT1 expressed in CHO-K1 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 4. | ALA863287 | B | Inhibitory activity towards human SGLT1 expressed in CHO-K1 cells at 10 uM | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA869549 | B | Inhibitory activity against SGLT1 expressed in CHO-K1 cells | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 6. | ALA868396 | B | Inhibition of SGLT1 expressed in CHO-K1 cells at 10 uM | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 7. | ALA2051077 | B | Inhibition of human SGLT1 expressed in CHO-K1 cells by [14C]AMG uptake assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 8. | ALA1811699 | B | Inhibition of human SGLT1 expressed in human 293 cells assessed as inhibition of [14C]-methyl-alpha-D-glucopyranoside uptake after 1.5 hrs by scintillation counting in presence of 25 % human plasma | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 9. | ALA1811700 | B | Inhibition of human SGLT1 expressed in african green monkey COS7 cells assessed as inhibition of [14C]-methyl-alpha-D-glucopyranoside uptake at 10 uM after 2 hrs by scintillation counting in presence of 25 % human plasma | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA1821170 | B | Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 11. | ALA947998 | B | Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]AMG accumulation | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 12. | ALA2065402 | B | Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 13. | ALA892510 | B | Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake at 50 uM | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 14. | ALA892512 | B | Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA2162521 | B | Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction of [14C]-AMG uptake | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 16. | ALA978802 | B | Reversal of inhibition of human SGLT1 expressed in xenopus laevis oocyte by measuring inhibition of methyl-alpha-D-[14C]glucopyranoside uptake after 1 hr assessed concentration required for 50% protective high affinity in presence of methyl-alpha-D-glucopyranoside relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 17. | ALA978803 | B | Inhibition of human SGLT1 expressed in xenopus laevis oocyte assessed as inhibition of methyl-alpha-D-[14C]glucopyranoside uptake at 75 pmol after 1 hr relative to control | Homo sapiens | 11 | assay format | Scientific Literature | ||
| 18. | ALA978804 | B | Inhibition of human SGLT1 expressed in xenopus laevis oocyte assessed as decrease in amount of SGLT1 protein level in oocyte plasma membrane at 75 pmol after 1 hr by Western blotting relative to control | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 19. | ALA978805 | B | Inhibition of human SGLT1 expressed in xenopus laevis oocyte assessed as decrease in phlorizin-induced capacitance at 75 pmol after 1 hr by relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA978806 | B | Inhibition of human SGLT1 expressed in xenopus laevis oocyte assessed as inhibition of methyl-alpha-D-[14C]glucopyranoside uptake at 75 pmol after 1 hr in presence of botulinum toxin B relative to control | Homo sapiens | 1 | assay format | Scientific Literature |
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