# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA654669 | Functional | Growth inhibition was measured against CHO cell line. | Cricetulus griseus | 20 | ALA1128500 | cell-based format | Scientific Literature | |
2. | ALA656378 | Functional | Effect on Hypusine formation in CHO cells at concentration 10 uM. | Cricetulus griseus | 19 | ALA1128500 | cell-based format | Scientific Literature | |
3. | ALA656379 | Functional | Effect on Hypusine formation in CHO cells at concentration 3 uM. | Cricetulus griseus | 19 | ALA1128500 | cell-based format | Scientific Literature | |
4. | ALA653163 | Functional | Effect on hypusine synthesis in CHO cells at concentration 10 uM. | Cricetulus griseus | 18 | ALA1128500 | cell-based format | Scientific Literature | |
5. | ALA653164 | Functional | Effect on hypusine synthesis in CHO cells at concentration 3 uM. | Cricetulus griseus | 20 | ALA1128500 | cell-based format | Scientific Literature | |
6. | ALA4358945 | Binding | Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabelled amino-butylidene incorporation in eIF5A using [3H]Spermidine trichloride as substrate after 90 to 120 mins in presence of eIF5A and 14 uM NAD+ by Topcount scintillation counting method | Homo sapiens | 21 | ALA4354863 | assay format | Scientific Literature | |
7. | ALA4358946 | Binding | Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabelled amino-butylidene incorporation in eIF5A using 2 uM of [3H]Spermidine trichloride as substrate after 90 to 120 mins in presence of eIF5A and 250 uM NAD+ by Topcount scintillation counting method | Homo sapiens | 3 | ALA4354863 | assay format | Scientific Literature | |
8. | ALA4358947 | Binding | Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabelled amino-butylidene incorporation in eIF5A using 100 uM of [3H]Spermidine trichloride as substrate after 90 to 120 mins in presence of eIF5A and 14 uM NAD+ by Topcount scintillation counting method | Homo sapiens | 1 | ALA4354863 | assay format | Scientific Literature | |
9. | ALA5043069 | Binding | Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assay | Homo sapiens | 30 | ALA5042482 | single protein format | Scientific Literature | |
10. | ALA5247164 | Binding | Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated for 120 mins in the presence of 14 uM NAD+ by radiometric assay | Homo sapiens | 22 | ALA5244276 | assay format | Scientific Literature | |
11. | ALA5247165 | Binding | Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated for 120 mins in the presence of 250 uM NAD+ by radiometric assay | Homo sapiens | 9 | ALA5244276 | assay format | Scientific Literature |