| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2050902 | B | Inhibition of rat Cav2.2 expressed in HEK293 cells under inactivating depolarizing conditions at holding potential of -115mV and stepped to 0 mV once every 15 seconds by whole cell patch clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2050903 | B | Inhibition of rat Cav2.2 expressed in HEK293 cells at 0.3 uM under higher hyperdepolarizing conditions at holding potential of -115mV and stepped to 0 mV once every 15 seconds by whole cell patch clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA2050904 | B | Inhibition of rat Cav2.2 expressed in HEK293 cells at 0.3 uM under inactivating depolarizing conditions at holding potential of -115mV and stepped to 0 mV once every 15 seconds by whole cell patch clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1059631 | B | Inhibition of rat neuronal Cav2.2 channel | Rattus norvegicus | 17 | single protein format | Scientific Literature | ||
| 5. | ALA1074544 | B | Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting | Rattus norvegicus | 14 | tissue-based format | Scientific Literature | ||
| 6. | ALA1113105 | B | Inhibition of rat Cav2.2 channel expressed in HEK cells assessed as depolarization-induced calcium influx by fluorescence-based assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA1113106 | B | Inhibition of rat Cav2.2 channel expressed in 0.07 Hz frequency-stimulated HEK cells by whole-cell patch-clamp technique | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA1113107 | B | Inhibition of rat Cav2.2 channel expressed in 0.07 Hz frequency-stimulated HEK cells at 30 uM by whole-cell patch-clamp technique | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA1113108 | B | Inhibition of rat Cav2.2 channel expressed in 5 Hz frequency-stimulated HEK cells at 30 uM by whole-cell patch-clamp technique | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA2390342 | B | Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assay | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
| 11. | ALA2415331 | B | Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under hyperpolarized condition by whole cell patch-clamp manual electrophysiology assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA2415333 | B | Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under depolarized condition by whole cell patch-clamp manual electrophysiology assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA3096607 | B | Inhibition of rat Cav2.2-mediated calcium flux expressed in HEK cells at 100 uM at 0.07 Hz by whole-cell patch-clamp assay relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3096608 | B | Inhibition of rat Cav2.2-mediated calcium flux expressed in HEK cells at 100 uM at 5 Hz by whole-cell patch-clamp assay relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3096609 | B | Inhibition of rat Cav2.2-mediated calcium flux expressed in HEK cells by FDSS assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3096610 | B | Inhibition of rat Cav2.2-mediated calcium flux expressed in HEK cells at 0.07 Hz by whole-cell patch-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3375974 | B | Inhibition of N-type Ca channel in Wistar rat DRG neuron at 100 nM by whole cell patch clamp technique relative to control | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
| 18. | ALA3375975 | B | Inhibition of N-type Ca channel in Wistar rat DRG neuron at 1 nM by whole cell patch clamp technique relative to control | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
| 19. | ALA3880754 | B | Antagonist activity at rat alpha1B N-type calcium channel expressed in HEK293 cells assessed as 0.067 Hz current frequency dependent channel blocking for 2 mins in presence of Ba2+ by whole-cell patch clamp assay | Rattus norvegicus | 33 | cell-based format | Patent Bioactivity Data | ||
| 20. | ALA3880755 | B | Antagonist activity at rat alpha1B N-type Ca2+ channel expressed in HEK293 cells assessed as 0.2 Hz current frequency dependent channel blocking for 2 mins in presence of Ba2+ by whole-cell patch clamp assay | Rattus norvegicus | 33 | cell-based format | Patent Bioactivity Data |
The page will load shortly, Thanks for your patience!