# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA658311 | F | Transcriptional agonist activity in Chinese hamster ovary cells expressing human Estrogen Receptor alpha | Homo sapiens | 6 | ALA1145862 | cell-based format | Scientific Literature | |
2. | ALA658317 | F | Percent change in 17-beta-estradiol mediated transcriptional activation in CHO cells expressing human estrogen receptor alpha at 10e-6 M | Homo sapiens | 1 | ALA1145862 | cell-based format | Scientific Literature | |
3. | ALA658318 | F | Percent change in 17-beta-estradiol mediated transcriptional activation in CHO cells expressing human estrogen receptor alpha at 10e-6 M | Homo sapiens | 1 | ALA1145862 | cell-based format | Scientific Literature | |
4. | ALA877291 | F | Percent change in 17-beta-estradiol mediated transcriptional activation in CHO cells expressing human estrogen receptor alpha at 10e-7 M | Homo sapiens | 3 | ALA1145862 | cell-based format | Scientific Literature | |
5. | ALA676599 | F | Effective dose in ERalpha-MCF-7 cells | Homo sapiens | 1 | ALA1136115 | cell-based format | Scientific Literature | |
6. | ALA676600 | F | Efficacy in ER alpha-MCF-7 cells | Homo sapiens | 1 | ALA1136115 | cell-based format | Scientific Literature | |
7. | ALA679348 | F | Estrogenic activity in MCF-7-2a cells as percent activation of 10e-8 M estradiol | Homo sapiens | 8 | ALA1135829 | cell-based format | Scientific Literature | |
8. | ALA679352 | F | Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50% | Homo sapiens | 8 | ALA1135829 | cell-based format | Scientific Literature | |
9. | ALA677235 | B | Activation of the estrogen receptors of MCF-7-2a cells at 10e-6 M. | 22 | ALA1136050 | assay format | Scientific Literature | ||
10. | ALA677860 | B | Percent relative binding affinity for estrogen receptor ligand binding domain expressed in BL21 cells at 2C | Escherichia coli | 11 | ALA1145825 | cell-based format | Scientific Literature | |
11. | ALA677861 | B | Percent relative binding affinity for estrogen receptor ligand binding domain expressed in BL21 cells at 25 degree C | Escherichia coli | 11 | ALA1145825 | cell-based format | Scientific Literature | |
12. | ALA677862 | B | Binding of [3H]E2 alkyl ester to human estrogen receptor alpha ligand binding domain expressed in Escherichia coli | Homo sapiens | 6 | ALA1145034 | assay format | Scientific Literature | |
13. | ALA677863 | B | In vitro displacement of 0.5 nM [3H]E2 from human Estrogen receptor alpha at 10 uM | Homo sapiens | 4 | ALA1136750 | single protein format | Scientific Literature | |
14. | ALA677864 | B | Affinity for human estrogen receptor alpha | Homo sapiens | 2 | ALA1136473 | single protein format | Scientific Literature | |
15. | ALA677865 | B | Binding affinity for Estrogen receptor alpha | Homo sapiens | 5 | ALA1136709 | single protein format | Scientific Literature | |
16. | ALA677866 | F | Agonist effect on transcriptional activation in HEC-1 cells expressing Estrogen receptor alpha at 10e-6 M | Homo sapiens | 5 | ALA1145083 | cell-based format | Scientific Literature | |
17. | ALA677867 | F | Antagonist effect on transcriptional activation in HEC-1 cells expressing Estrogen receptor alpha at 10e-6 M with 10e-9 M estradiol | Homo sapiens | 5 | ALA1145083 | cell-based format | Scientific Literature | |
18. | ALA677868 | F | Agonist effect on transcriptional activation in HEC-1 cells expressing Estrogen receptor alpha at 10e-8 M | Homo sapiens | 5 | ALA1145083 | cell-based format | Scientific Literature | |
19. | ALA677869 | B | log(I/IC50) against estrogen receptor alpha | Homo sapiens | 8 | ALA1136444 | single protein format | Scientific Literature | |
20. | ALA677870 | B | Binding affinity for estrogen receptor alpha | Homo sapiens | 8 | ALA1136444 | single protein format | Scientific Literature |