| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA698854 | B | Inhibitory activity against Interleukin 1d using [3H]IL-1-alpha at 10e5 (M) | 1 | single protein format | Scientific Literature | |||
| 2. | ALA3766039 | B | Inhibition of IL-1 receptor (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA3825660 | B | Activation of IL-1R in human monocytes assessed as inhibition of IL-1beta-stimulated TNF-alpha production preincubated for 30 mins prior to IL-1beta stimulation at 1 uM measured after 6 hrs by immunoassay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4184517 | B | Displacement of [125I]interleukin-1beta from human recombinant IL-1 receptor at 10 uM after 20 hrs by scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4195489 | B | Inhibition of IL1R in TLR null HEK-blue cells assessed as decrease in IL-1beta-stimulated NF-kappaB activation-mediated SEAP production after 24 hrs by Quanti-blue-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4367442 | B | Inhibition of IL1R in human monocytes assessed as reduction in IL1beta-induced TNFalpha production | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4622265 | B | Antagonist activity at IL1R in human PBMC assessed as inhibition of IL1beta-induced TNFalpha production preincubated for 30 mins followed by IL1beta addition and measured after 20 hrs by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4667517 | B | Displacement of [125I]-Interleukin 1beta from human interleukin IL-1 R1 receptor assessed as residual binding level for radioligand at 10 uM incubated for 1200 mins by scintillation counting analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4671110 | B | Displacement of [125I]-Interleukin 1beta from human interleukin IL-1 R1 receptor at 10 uM incubated for 120 mins by scintillation counting analysis relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 10. | ALA4884609 | B | Interleukin IL-1 R1 Eurofins-Panlabs radioligand binding assay | Homo sapiens | 3 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 11. | ALA5228023 | B | Inhibition of human IL1-R1 assessed as dissociation constant incubated for 5 mins by SPR analysis | Homo sapiens | 1 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!