| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA829171 | F | Effective concentration to antagonise accessory gene regulator C2 of Staphylococcus aureus | Staphylococcus aureus | 1 | ALA1138741 | assay format | Scientific Literature | |
| 2. | ALA829172 | F | Effective concentration to antagonise accessory gene regulator C3 of Staphylococcus aureus | Staphylococcus aureus | 1 | ALA1138741 | assay format | Scientific Literature | |
| 3. | ALA829173 | F | Effective concentration to antagonise accessory gene regulator C4 of Staphylococcus aureus | Staphylococcus aureus | 1 | ALA1138741 | assay format | Scientific Literature | |
| 4. | ALA841798 | F | Effective concentration to antagonise accessory gene regulator C1 of Staphylococcus aureus; range = 9-11 uM | Staphylococcus aureus | 1 | ALA1138741 | assay format | Scientific Literature | |
| 5. | ALA831083 | B | Concentration required to inhibit quorum sensor of Staphylococcus aureus | Staphylococcus aureus | 9 | ALA1138741 | single protein format | Scientific Literature | |
| 6. | ALA832959 | F | Antagonistic concentration for accessory gene regulator C1 of Staphylococcus aureus | Staphylococcus aureus | 3 | ALA1138741 | assay format | Scientific Literature | |
| 7. | ALA832960 | F | Concentration required to antagonise accessory gene regulator C2 of Staphylococcus aureus | Staphylococcus aureus | 2 | ALA1138741 | assay format | Scientific Literature | |
| 8. | ALA832961 | F | Concentration required to antagonise accessory gene regulator C3 of Staphylococcus aureus | Staphylococcus aureus | 2 | ALA1138741 | assay format | Scientific Literature | |
| 9. | ALA832141 | F | Concentration required to antagonise accessory gene regulator C4 of Staphylococcus aureus | Staphylococcus aureus | 2 | ALA1138741 | assay format | Scientific Literature | |
| 10. | ALA3239045 | B | Binding affinity to AgrC in Staphylococcus aureus assessed as disruption of membrane dipole potential by di-8-ANEPPS fluorescence assay | Staphylococcus aureus | 6 | ALA3232797 | assay format | Scientific Literature | |
| 11. | ALA4154604 | B | Inhibition of AIP-stimulated quorum sensing system AgrC activation in Staphylococcus aureus RN10829 harboring P3:blaZ fusion assessed as reduction in beta-lactamse activity at 5 ug/ml preincubated with organism followed by AIP addition measured after 45 mins by nitrocefin hydrolysis assay | Staphylococcus aureus | 27 | ALA4152251 | single protein format | Scientific Literature | |
| 12. | ALA4154605 | B | Inhibition of AIP-stimulated quorum sensing system AgrC activation in Staphylococcus aureus RN10829 harboring P3:blaZ fusion assessed as reduction in beta-lactamse activity preincubated with organism followed by AIP addition measured after 45 mins by nitrocefin hydrolysis assay | Staphylococcus aureus | 8 | ALA4152251 | single protein format | Scientific Literature | |
| 13. | ALA4270014 | B | Inhibition of recombinant Staphylococcus aureus AgrC autophosphorylation expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by [gamma-32P]-ATP addition measured after 15 mins by coomassie-brilliant blue staining based SDS PAGE/autoradiographic analysis | Staphylococcus aureus | 2 | ALA4266038 | assay format | Scientific Literature | |
| 14. | ALA4403575 | B | Inhibition of AgrC in mid-exponential phase Staphylococcus aureus RN6390B assessed as beta-lactamase activity incubated for 80 mins by spectrophotometric method | Staphylococcus aureus | 3 | ALA4402540 | single protein format | Scientific Literature | |
| 15. | ALA4403576 | B | Activation of AgrC in early exponential phase Staphylococcus aureus RN6390B assessed as beta-lactamase activity incubated for 55 mins by spectrophotometric method | Staphylococcus aureus | 1 | ALA4402540 | single protein format | Scientific Literature | |
| 16. | ALA4403577 | B | Activation of AgrC in early exponential phase Staphylococcus aureus SA502A assessed as beta-lactamase activity incubated for 55 mins by spectrophotometric method | Staphylococcus aureus | 1 | ALA4402540 | single protein format | Scientific Literature | |
| 17. | ALA4403578 | B | Inhibition of AgrC in mid-exponential phase Staphylococcus aureus SA502A assessed as beta-lactamase activity incubated for 80 mins by spectrophotometric method | Staphylococcus aureus | 1 | ALA4402540 | single protein format | Scientific Literature | |
| 18. | ALA4403579 | B | Inhibition of AgrC in mid-exponential phase Staphylococcus aureus RN8463 assessed as beta-lactamase activity incubated for 80 mins by spectrophotometric method | Staphylococcus aureus | 2 | ALA4402540 | single protein format | Scientific Literature |
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