# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1613792 | Functional | PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature. (Class of assay: confirmatory) | Homo sapiens | 3,280 | ALA1201862 | assay format | PubChem BioAssays | |
2. | ALA1614481 | Functional | PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) | Homo sapiens | 6,208 | ALA1201862 | assay format | PubChem BioAssays | |
3. | ALA1613992 | Functional | PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) | Homo sapiens | 10,316 | ALA1201862 | assay format | PubChem BioAssays | |
4. | ALA1613995 | Functional | PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature. (Class of assay: confirmatory) [Related pubchem assays: 902 ] | Homo sapiens | 6,267 | ALA1201862 | assay format | PubChem BioAssays | |
5. | ALA1052162 | Binding | Induction of p53 in human HCT116 cells coexpressing pp53TA-luc assessed as inhibition of cell proliferation after 8 hrs by firefly/renilla luciferase reporter assay | Homo sapiens | 7 | ALA1154659 | cell-based format | Scientific Literature | |
6. | ALA1052166 | Binding | Induction of p53-Ser15 phosphorylation in human HCT116 cells after 24 hrs | Homo sapiens | 2 | ALA1154659 | cell-based format | Scientific Literature | |
7. | ALA991464 | Binding | Effect on p53-Ser-15 phosphorylation in ataxia telangiectasia mutated and Rad3 related-deficient human HCT116 cells at 1 nM after 1 hr by Western blotting | 1 | ALA1156531 | cell-based format | Scientific Literature | ||
8. | ALA991465 | Binding | Effect on p53-Ser-15 phosphorylation in ataxia telangiectasia mutated and Rad3 related-deficient human HCT116 cells at 3 nM after 1 hr by Western blotting | 1 | ALA1156531 | cell-based format | Scientific Literature | ||
9. | ALA939816 | Binding | Increase in p53-Ser15 phosphorylation in human HeLa cells at 100 uM by Western blotting | Homo sapiens | 1 | ALA1141027 | cell-based format | Scientific Literature | |
10. | ALA904416 | Functional | Stabilization of p53 in RPE cells at 1 uM after 24 hrs by Western blotting | Homo sapiens | 25 | ALA1144520 | cell-based format | Scientific Literature | |
11. | ALA904417 | Functional | Stabilization of p53 in RPE cells at 5 to 10 uM after 24 hrs by Western blotting relative to HL198C | Homo sapiens | 25 | ALA1144520 | cell-based format | Scientific Literature | |
12. | ALA1226577 | Binding | Effect on p53 expressed in HEK293 cells assessed as effect on p53-p53 interaction complexes in presence of camptothecin by EYFP and/or YFP Venus fragment based reporter gene assay | 7 | ALA1221184 | cell-based format | Scientific Literature | ||
13. | ALA1226583 | Binding | Inhibition of p53 expressed in HEK293 cells assessed as effect on p53-p53 interaction complexes in presence of camptothecin by EYFP and/or YFP Venus fragment based reporter gene assay | 2 | ALA1221184 | cell-based format | Scientific Literature | ||
14. | ALA1226716 | Binding | Inhibition of p53 phosphorylation at Ser15 in human BJ cells-induced senescence with reterovirus infection expressing TRF2-delta-B-delta-M/EGFP | Homo sapiens | 1 | ALA1221185 | cell-based format | Scientific Literature | |
15. | ALA1249424 | Binding | Binding affinity to p53 assessed as reduction in mitochondrial-bound p53 level at 10 uM | 1 | ALA1240314 | single protein format | Scientific Literature | ||
16. | ALA1249425 | Binding | Binding affinity to p53 assessed as reduction in mitochondrial-bound p53 level at 25 uM | 1 | ALA1240314 | single protein format | Scientific Literature | ||
17. | ALA1249426 | Binding | Binding affinity to p53 assessed as reduction in mitochondrial-bound p53 level at 50 uM | 1 | ALA1240314 | single protein format | Scientific Literature | ||
18. | ALA1249427 | Binding | Binding affinity to p53 transfected in human T293 cells assessed as reduction in p53 bound-Bcl-xL at 15 uM after 48 hrs | 1 | ALA1240314 | cell-based format | Scientific Literature | ||
19. | ALA1249428 | Binding | Binding affinity to p53 transfected in human T293 cells assessed as reduction in p53 bound-Bcl-2 at 15 uM after 48 hrs | 1 | ALA1240314 | cell-based format | Scientific Literature | ||
20. | ALA1249761 | Binding | Inhibition of p53-dependent transactivation of p21 in gamma-stimulated human ConA cells | Homo sapiens | 2 | ALA1240314 | cell-based format | Scientific Literature |