# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA904416 | F | Stabilization of p53 in RPE cells at 1 uM after 24 hrs by Western blotting | Homo sapiens | 25 | ALA1144520 | cell-based format | Scientific Literature | |
2. | ALA904417 | F | Stabilization of p53 in RPE cells at 5 to 10 uM after 24 hrs by Western blotting relative to HL198C | Homo sapiens | 25 | ALA1144520 | cell-based format | Scientific Literature | |
3. | ALA939816 | B | Increase in p53-Ser15 phosphorylation in human HeLa cells at 100 uM by Western blotting | Homo sapiens | 1 | ALA1141027 | cell-based format | Scientific Literature | |
4. | ALA991464 | B | Effect on p53-Ser-15 phosphorylation in ataxia telangiectasia mutated and Rad3 related-deficient human HCT116 cells at 1 nM after 1 hr by Western blotting | 1 | ALA1156531 | cell-based format | Scientific Literature | ||
5. | ALA991465 | B | Effect on p53-Ser-15 phosphorylation in ataxia telangiectasia mutated and Rad3 related-deficient human HCT116 cells at 3 nM after 1 hr by Western blotting | 1 | ALA1156531 | cell-based format | Scientific Literature | ||
6. | ALA1052162 | B | Induction of p53 in human HCT116 cells coexpressing pp53TA-luc assessed as inhibition of cell proliferation after 8 hrs by firefly/renilla luciferase reporter assay | Homo sapiens | 7 | ALA1154659 | cell-based format | Scientific Literature | |
7. | ALA1052166 | B | Induction of p53-Ser15 phosphorylation in human HCT116 cells after 24 hrs | Homo sapiens | 2 | ALA1154659 | cell-based format | Scientific Literature | |
8. | ALA1226577 | B | Effect on p53 expressed in HEK293 cells assessed as effect on p53-p53 interaction complexes in presence of camptothecin by EYFP and/or YFP Venus fragment based reporter gene assay | 7 | ALA1221184 | cell-based format | Scientific Literature | ||
9. | ALA1226583 | B | Inhibition of p53 expressed in HEK293 cells assessed as effect on p53-p53 interaction complexes in presence of camptothecin by EYFP and/or YFP Venus fragment based reporter gene assay | 2 | ALA1221184 | cell-based format | Scientific Literature | ||
10. | ALA1226716 | B | Inhibition of p53 phosphorylation at Ser15 in human BJ cells-induced senescence with reterovirus infection expressing TRF2-delta-B-delta-M/EGFP | Homo sapiens | 1 | ALA1221185 | cell-based format | Scientific Literature | |
11. | ALA1249424 | B | Binding affinity to p53 assessed as reduction in mitochondrial-bound p53 level at 10 uM | 1 | ALA1240314 | single protein format | Scientific Literature | ||
12. | ALA1249425 | B | Binding affinity to p53 assessed as reduction in mitochondrial-bound p53 level at 25 uM | 1 | ALA1240314 | single protein format | Scientific Literature | ||
13. | ALA1249426 | B | Binding affinity to p53 assessed as reduction in mitochondrial-bound p53 level at 50 uM | 1 | ALA1240314 | single protein format | Scientific Literature | ||
14. | ALA1249427 | B | Binding affinity to p53 transfected in human T293 cells assessed as reduction in p53 bound-Bcl-xL at 15 uM after 48 hrs | 1 | ALA1240314 | cell-based format | Scientific Literature | ||
15. | ALA1249428 | B | Binding affinity to p53 transfected in human T293 cells assessed as reduction in p53 bound-Bcl-2 at 15 uM after 48 hrs | 1 | ALA1240314 | cell-based format | Scientific Literature | ||
16. | ALA1249761 | B | Inhibition of p53-dependent transactivation of p21 in gamma-stimulated human ConA cells | Homo sapiens | 2 | ALA1240314 | cell-based format | Scientific Literature | |
17. | ALA1249841 | B | Inhibition of p53-mediated apoptosis in human WI38 cells assessed as cell survival at 10 uM after 24 hrs by methylene blue assay | Homo sapiens | 1 | ALA1240314 | cell-based format | Scientific Literature | |
18. | ALA1249843 | B | Inhibition of p53-mediated apoptosis in human Saos-2 cells harboring p53 expressing lentiviral vector assessed as cell survival at 10 uM after 48 hrs by methylene blue assay | Homo sapiens | 1 | ALA1240314 | cell-based format | Scientific Literature | |
19. | ALA1249847 | B | Inhibition of p53-mediated transactivation of promoter bax in human H1299 cells at 10 uM after 48 hrs by luciferase reporter assay | Homo sapiens | 1 | ALA1240314 | cell-based format | Scientific Literature | |
20. | ALA1249848 | B | Inhibition of p53-mediated transactivation of promoter cyclin G in human H1299 cells at 10 uM after 48 hrs by luciferase reporter assay | Homo sapiens | 1 | ALA1240314 | cell-based format | Scientific Literature |