| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1805065 | B | Competitive inhibition of His-tagged FimH carbohydrate recognizing domain expressed in Escherichia coli HM125 using ABTS-substrate after 3 hrs by calorimetric assay | Escherichia coli | 18 | assay format | Scientific Literature | ||
| 2. | ALA1805066 | B | Ratio IC50 for compound to IC50 for n-heptyl R-D-mannopyranoside for His-tagged FimH expressed in Escherichia coli HM125 | Escherichia coli | 18 | assay format | Scientific Literature | ||
| 3. | ALA1805067 | F | Antagonist activity at Escherichia coli UT189 FimH in guinea pig red blood cells assessed as disaggregation of bacteria after 600 secs by aggregometry assay | Escherichia coli | 18 | cell-based format | Scientific Literature | ||
| 4. | ALA1919133 | B | Antagonist activity at Escherichia coli recombinant C-terminal 6His-tagged FimH-CRD with a C-terminal thrombin cleavage site expressed in Escherichia coli HM125 assessed as inhibition of streptavidin-horseradish peroxidase conjugated TM-PAA polymer binding after 3 hrs by spectrophotometry | Escherichia coli | 31 | assay format | Scientific Literature | ||
| 5. | ALA1919134 | B | Ratio of compound IC50 to n-heptyl alpha-D-mannopyranoside IC50 for Escherichia coli recombinant C-terminal 6His-tagged FimH-CRD with a C-terminal thrombin cleavage site expressed in Escherichia coli HM125 assessed as inhibition of streptavidin-horseradish peroxidase conjugated TM-PAA polymer binding after 3 hrs by spectrophotometry | Escherichia coli | 30 | assay format | Scientific Literature | ||
| 6. | ALA2399352 | B | Binding affinity to Escherichia coli FimH assessed as dissociation constant by ITC analysis | Escherichia coli | 1 | single protein format | Scientific Literature | ||
| 7. | ALA2399353 | B | Binding affinity to Escherichia coli K-12 FimH assessed as dissociation constant by SPR analysis | Escherichia coli K-12 | 1 | single protein format | Scientific Literature | ||
| 8. | ALA2399354 | B | Binding affinity to Escherichia coli FimH assessed as decrease in RNaseB binding after 1 hr by competitive ELISA | Escherichia coli | 13 | single protein format | Scientific Literature | ||
| 9. | ALA5140886 | B | Binding affinity to Escherichia coli FimH assessed as dissociation constant by SPR analysis | Escherichia coli | 3 | single protein format | Scientific Literature | ||
| 10. | ALA5140887 | B | Relative inhibitory potency, ratio of methyl alpha-D-mannose Kd to compound Kd for binding affinity to C-terminal His-tagged truncated Escherichia coli FimH by SPR analysis | Escherichia coli | 3 | single protein format | Scientific Literature | ||
| 11. | ALA5140888 | B | Relative inhibitory potency, ratio of methyl alpha-D-mannose Kd to compound Kd for binding affinity to Escherichia coli FimH by ELISA assay | Escherichia coli | 2 | single protein format | Scientific Literature | ||
| 12. | ALA5140889 | B | Inhibition of Escherichia coli UTI89 FimH by hemagglutination assay | Escherichia coli | 10 | single protein format | Scientific Literature | ||
| 13. | ALA3130557 | B | Binding affinity to Escherichia coli J96 FimH lectin domain expressed in Escherichia coli C43 (DE3) by SAXS analysis | Escherichia coli J96 | 1 | assay format | Scientific Literature | ||
| 14. | ALA3130559 | B | Binding affinity to Escherichia coli J96 FimH lectin domain expressed in Escherichia coli C43 (DE3) by NMR analysis | Escherichia coli J96 | 1 | assay format | Scientific Literature | ||
| 15. | ALA3130561 | B | Binding affinity to Escherichia coli J96 wild type FimH lectin domain expressed in Escherichia coli C43 (DE3) by reverse ITC analysis | Escherichia coli J96 | 1 | assay format | Scientific Literature | ||
| 16. | ALA3130562 | B | Binding affinity to Escherichia coli J96 wild type FimH lectin domain expressed in Escherichia coli C43 (DE3) by direct ITC analysis | Escherichia coli J96 | 1 | assay format | Scientific Literature | ||
| 17. | ALA3598576 | B | Binding affinity to Escherichia coli FimH | Escherichia coli | 5 | single protein format | Scientific Literature | ||
| 18. | ALA3598577 | B | Antagonist activity at Escherichia coli FimH assessed as inhibition of yeast agglutination | Escherichia coli | 2 | single protein format | Scientific Literature | ||
| 19. | ALA3598578 | B | Inhibition of Escherichia coli FimH relative to methyl alpha-D-mannopyranoside | Escherichia coli | 5 | single protein format | Scientific Literature | ||
| 20. | ALA3598579 | B | Inhibition of Escherichia coli FimH relative to heptyl alpha-D-mannopyranoside | Escherichia coli | 3 | single protein format | Scientific Literature |
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