| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA839581 | A | Effect on coumarin 7-hydroxylation by human Cytochrome P-450 2A6 | Homo sapiens | 60 | single protein format | Scientific Literature | ||
| 2. | ALA826388 | A | Michaelis-Menten constant of compound against human cytochrome P450 2A6 enzyme | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA832816 | A | Inhibitory concentration against human cytochrome P450 2A6 | Homo sapiens | 48 | single protein format | Scientific Literature | ||
| 4. | ALA829411 | A | Inhibitory concentration value against human cytochrome P-450 2A6 | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 5. | ALA836206 | A | Inhibition of CYP2A6 at 2 uM, assessed by effect on rate of oxidation of coumarin 7-hydroxylation upon incubation with human liver microsomes | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 6. | ALA836209 | A | Inhibition of CYP2A6 at 20 uM assessed by effect on rate of oxidation of coumarin 7-hydroxylation upon incubation with human liver microsomes | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 7. | ALA859093 | A | Binding constant for compound binding to CYP2A6 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA910615 | A | Displacement of coumarin from CYP2A6 at 100 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 9. | ALA910617 | A | Inhibition of human CYP2A6 | Homo sapiens | 29 | single protein format | Scientific Literature | ||
| 10. | ALA910628 | A | Inhibition of human CYP2A6 measured as half life | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 11. | ALA909371 | A | Inhibition of human CYP2A6 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 12. | ALA2045904 | A | Inhibition of human CYP2A6-mediated coumarin 7-hydroxylation in liver microsomes at 10 uM coincubated with substrate | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 13. | ALA2045905 | A | Inhibition of human CYP2A6-mediated coumarin 7-hydroxylation in liver microsomes at 10 uM preincubated for 15 mins prior substrate addition | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 14. | ALA2092287 | A | Inhibition of CYP2A6 at 5 uM | 1 | single protein format | Scientific Literature | |||
| 15. | ALA1821056 | A | Inhibition of CYP2A6 | 1 | single protein format | Scientific Literature | |||
| 16. | ALA2034418 | A | Inhibition of CYP2A6 in human liver microsomes up to 100 uM | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 17. | ALA1909133 | B | DRUGMATRIX: CYP450, 2A6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | 871 | cell-based format | DrugMatrix | |||
| 18. | ALA1924632 | A | Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 10 mins by plate reader | Homo sapiens | 11 | microsome format | Scientific Literature | ||
| 19. | ALA1924633 | A | Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 30 mins preincubation by plate reader | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 20. | ALA1924634 | A | Irreversible inhibition of CYP2A6 in human liver microsomes assessed as coumarin 7-hydroxylation activity in presence of NADPH | Homo sapiens | 3 | microsome format | Scientific Literature |
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