# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA829719 | F | Effective concentration for glucokinase activity; NA - No activation at 30 uM | Rattus norvegicus | 2 | ALA1142024 | assay format | Scientific Literature | |
2. | ALA829722 | F | Effective concentration for glucokinase activation; NA - No activation at 30 uM | Rattus norvegicus | 2 | ALA1142024 | assay format | Scientific Literature | |
3. | ALA829031 | F | Effective concentration for glucokinase activation with 5 mM glucose | Rattus norvegicus | 28 | ALA1142024 | assay format | Scientific Literature | |
4. | ALA829033 | F | Effective concentration for glucokinase activation with 15 mM glucose | Rattus norvegicus | 2 | ALA1142024 | assay format | Scientific Literature | |
5. | ALA835312 | B | Maximal activation of glucokinase; NA - No activation at 30 uM | Rattus norvegicus | 4 | ALA1142024 | single protein format | Scientific Literature | |
6. | ALA835313 | B | Maximal activation of glucokinase at 5 mM glucose | Rattus norvegicus | 28 | ALA1142024 | single protein format | Scientific Literature | |
7. | ALA835314 | B | Maximal activation of glucokinase at 15 mM glucose | Rattus norvegicus | 2 | ALA1142024 | single protein format | Scientific Literature | |
8. | ALA1053632 | B | Activation of glucokinase-mediated of glucose phosphorylation in Sprague-Dawley rat hepatocytes assessed as release of [3H]H2O from [2-3H]glucose at 30 uM after 3 hrs | Rattus norvegicus | 13 | ALA1155225 | cell-based format | Scientific Literature | |
9. | ALA1167930 | B | Induction of glucokinase-mediated 2-deoxy-D-[3H]glucose uptake in Sprague-Dawley rat hepatocytes after 4 hrs by liquid scintillation counting relative to control | Rattus norvegicus | 1 | ALA1165956 | cell-based format | Scientific Literature | |
10. | ALA1167931 | B | Induction of glucokinase-mediated 2-deoxy-D-[3H]glucose uptake in Sprague-Dawley rat hepatocytes after 4 hrs by liquid scintillation countingl | Rattus norvegicus | 1 | ALA1165956 | cell-based format | Scientific Literature | |
11. | ALA1167934 | B | Induction of glucokinase-mediated glucose accumulation in Sprague-Dawley rat hepatocytes at 1 uM after 6 hrs relative to control | Rattus norvegicus | 1 | ALA1165956 | cell-based format | Scientific Literature | |
12. | ALA2168596 | B | Activation of glucokinase in rat INS-1 cells assessed as stimulation of glucose-induced insulin secretion | Rattus norvegicus | 2 | ALA2163316 | cell-based format | Scientific Literature | |
13. | ALA2168597 | B | Ratio of EC50 for activation of glucokinase in rat INS-1 cells to EC50 for in-vitro activation of rat glucokinase | Rattus norvegicus | 11 | ALA2163316 | cell-based format | Scientific Literature | |
14. | ALA2166289 | B | Induction of glucokinase translocation from nucleus to cytoplasm in cryopreserved rat hepatocytes after 1 hr by Hoechst staining-based fluorescence microscopic analysis | Rattus norvegicus | 2 | ALA2163316 | cell-based format | Scientific Literature | |
15. | ALA2166290 | B | Activation of glucokinase in Sprague-Dawley rat islets assessed as enhancement of glucose-stimulated insulin secretion after 60 mins by enzyme immunoassay | Rattus norvegicus | 1 | ALA2163316 | single protein format | Scientific Literature | |
16. | ALA2166291 | B | Activation of glucokinase in Sprague-Dawley rat islets assessed as enhancement of glucose-stimulated insulin secretion at 100 times EC50 concentration after 60 mins by enzyme immunoassay | Rattus norvegicus | 1 | ALA2163316 | single protein format | Scientific Literature | |
17. | ALA2215682 | B | Activation of recombinant rat glucokinase assessed measuring rate of glucose 6-phosphate formation using G6PDH/NADP coupling | Rattus norvegicus | 1 | ALA2203262 | single protein format | Scientific Literature | |
18. | ALA3095486 | B | Activation of glucokinase in Wistar rat hepatocytes assessed as nuclear to cytosolic translocation of protein by immunofluorescence assay | Rattus norvegicus | 1 | ALA3091348 | cell-based format | Scientific Literature | |
19. | ALA3095509 | B | Activation of glucokinase in rat INS-1 cells assessed as glucose-stimulated insulin secretion | Rattus norvegicus | 2 | ALA3091348 | cell-based format | Scientific Literature | |
20. | ALA3223667 | B | Activation of rat glucokinase | Rattus norvegicus | 8 | ALA3217627 | single protein format | Scientific Literature |